公开(公告)号：EP0346983A3

公开(公告)日：1990-01-03

申请号：EP89201495.2

申请日：1989-06-08

申请人： COÖPERATIEVE VERENIGING SUIKER UNIE U.A.

发明人： Van Nispen, Joannes Gerardus Maria ,  Jonker, Ronald ,  Meyer, Pieter D c/o Coop. Ver. Suiker Unie U.A. ,  Koerts, Kees c/o Coop. Ver. Suiker Unie U.A.

IPC分类号： C12P7/56

CPC分类号： B01D61/58 ,  B01D61/145 ,  B01D61/422 ,  B01D61/445 ,  C12M47/10 ,  C12P7/56 ,  C12R1/07 ,  Y10S435/832 ,  Y10S435/856

摘要： The present invention relates to a process for the fermenta­tive preparation of lactic acid, by allowing a sterilized growth medium to be continuously fermented in a reaction vessel by a culture of bacilli of the genus Bacillus , which form lactic acid, keeping the pH of the reaction mixture at 3 to 9 with an aqueous solution of XOH (where X is NH₄ or a metal whose hydroxide and whose salt of lactic acid are watersoluble), subjecting the fer­mented reaction mixture to an ultrafiltration, recycling the reten­tate to the reaction vessel, and concentrating the permeate and subsequently subjecting it to an electrodialysis wherein bipolar membranes are used, in which process the lactate is decomposed into the lactic acid and XOH.

公开(公告)号：EP0346983B1

公开(公告)日：1994-03-09

申请号：EP89201495.2

申请日：1989-06-08

申请人： COÖPERATIEVE VERENIGING SUIKER UNIE U.A.

发明人： Van Nispen, Joannes Gerardus Maria ,  Jonker, Ronald ,  Meyer, Pieter D c/o Coop. Ver. Suiker Unie U.A. ,  Koerts, Kees c/o Coop. Ver. Suiker Unie U.A.

IPC分类号： C12P7/56

CPC分类号： B01D61/58 ,  B01D61/145 ,  B01D61/422 ,  B01D61/445 ,  C12M47/10 ,  C12P7/56 ,  C12R1/07 ,  Y10S435/832 ,  Y10S435/856

摘要： The present invention relates to a process for the fermentative preparation of lactic acid, by allowing a sterilized growth medium to be continuously fermented in a reaction vessel by a culture of bacilli of the genus Bacillus, which form lactic acid, keeping the pH of the reaction mixture at 3 to 9 with an aqueous solution of XOH (where X is NH4 or a metal whose hydroxide and whose salt of lactic acid are watersoluble), subjecting the fermented reaction mixture to an ultrafiltration, recycling the retentate to the reaction vessel, and concentrating the permeate and subsequently subjecting it to an electrodialysis wherein bipolar membranes are used, in which process the lactate is decomposed into the lactic acid and XOH.

公开(公告)号：EP0346983A2

公开(公告)日：1989-12-20

申请号：EP89201495.2

申请日：1989-06-08

申请人： COÖPERATIEVE VERENIGING SUIKER UNIE U.A.

发明人： Van Nispen, Joannes Gerardus Maria ,  Jonker, Ronald ,  Meyer, Pieter D c/o Coop. Ver. Suiker Unie U.A. ,  Koerts, Kees c/o Coop. Ver. Suiker Unie U.A.

IPC分类号： C12P7/56

CPC分类号： B01D61/58 ,  B01D61/145 ,  B01D61/422 ,  B01D61/445 ,  C12M47/10 ,  C12P7/56 ,  C12R1/07 ,  Y10S435/832 ,  Y10S435/856

摘要： The present invention relates to a process for the fermenta­tive preparation of lactic acid, by allowing a sterilized growth medium to be continuously fermented in a reaction vessel by a culture of bacilli of the genus Bacillus , which form lactic acid, keeping the pH of the reaction mixture at 3 to 9 with an aqueous solution of XOH (where X is NH₄ or a metal whose hydroxide and whose salt of lactic acid are watersoluble), subjecting the fer­mented reaction mixture to an ultrafiltration, recycling the reten­tate to the reaction vessel, and concentrating the permeate and subsequently subjecting it to an electrodialysis wherein bipolar membranes are used, in which process the lactate is decomposed into the lactic acid and XOH.

摘要翻译： 本发明涉及通过使形成乳酸的芽孢杆菌属杆菌的培养物在灭菌的生长培养基中在反应容器中连续发酵而使乳酸发酵的方法，保持反应的pH 混合物在3〜9℃下与XOH水溶液（其中X为NH 4或其氢氧化物及其乳酸盐为水溶性的金属），使发酵反应混合物进行超滤，将滞留物再循环至反应容器中，并浓缩 渗透物并随后使其进行电渗析，其中使用双极性膜，其中乳酸盐分解成乳酸和XOH。