公开(公告)号：EP1343886A2

公开(公告)日：2003-09-17

申请号：EP01984164.2

申请日：2001-07-10

申请人： CORIXA CORPORATION

发明人： WANG, Tongtong ,  WATANABE, Yoshihiro ,  HENDERSON, Robert, A. ,  JOHNSON, Jeffrey, C. ,  RETTER, Marc, W. ,  DURHAM,Margarita ,  CARTER, Darrick ,  FANGER, Gary, Richard ,  VEDVICK, Thomas, S. ,  BANGUR, Chaitanya, S. ,  MCNABB, Andria ,  WANG, Aijun ,  FANGER, Neil ,  SWITZER, Ann ,  MCNEILL, Patricia, D. ,  CLAPPER, Jonathan, D.

IPC分类号： C12N15/12 ,  C07K14/47 ,  C07K14/705 ,  C07K16/30 ,  G01N33/574 ,  G01N33/68 ,  C12Q1/68 ,  C12N15/62 ,  C12N5/10 ,  A61K38/17 ,  A61K48/00 ,  A61K39/395 ,  A61P35/00

CPC分类号： C07K14/47 ,  A61K38/00 ,  A61K2039/5154 ,  A61K2039/5156 ,  C07K2319/00

摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.

公开(公告)号：EP1446013A2

公开(公告)日：2004-08-18

申请号：EP02793857.0

申请日：2002-10-28

申请人： CORIXA CORPORATION

发明人： HENDERSON, Robert, A. ,  WANG, Tongtong ,  WATANABE, Yoshihiro ,  KALOS, Michael, D. ,  SLEATH, Paul, R. ,  JOHNSON, Jeffrey, C. ,  RETTER, Marc, W. ,  DURHAM, Margarita ,  CARTER, Darrick ,  FANGER, Gary, R. ,  VEDVICK, Thomas, S. ,  BANGUR, Chaitanya, S. ,  MCNABB, Andria

IPC分类号： A01N63/00 ,  A61K39/395 ,  A61K39/00

CPC分类号： C07K14/4748 ,  A61K38/00 ,  A61K2039/5154 ,  A61K2039/5156 ,  C07K14/47 ,  C07K2319/00 ,  C12Q1/6886 ,  C12Q2600/158

摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.