公开(公告)号：EP1319069A2

公开(公告)日：2003-06-18

申请号：EP01952390.1

申请日：2001-06-28

申请人： CORIXA CORPORATION

发明人： WANG, Tongtong ,  WANG, Aijun ,  SKEIKY, Yasir, A., W. ,  LI, Samuel, X. ,  KALOS, Michael, D. ,  HENDERSON, Robert, A. ,  MCNEILL, Patricia, D. ,  FANGER, Neil ,  RETTER, Marc, W. ,  DURHAM, Margarita ,  FANGER, Gary, Richard ,  VEDVICK, Thomas, S. ,  CARTER, Darrick ,  WATANABE, Yoshihiro ,  PECKHAM, David, W.

IPC分类号： C12N15/12 ,  C07K14/47 ,  C07K16/30 ,  G01N33/574 ,  C12Q1/68 ,  C12N5/08 ,  A61K38/17 ,  A61K31/711 ,  A61K39/395 ,  A61K35/14

CPC分类号： C07K16/3023 ,  C07K14/47 ,  C07K2317/21 ,  C07K2317/34

摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.

公开(公告)号：EP1319069B1

公开(公告)日：2008-05-21

申请号：EP01952390.1

申请日：2001-06-28

申请人： CORIXA CORPORATION

发明人： WANG, Tongtong ,  WANG, Aijun ,  SKEIKY, Yasir, A., W. ,  LI, Samuel, X. ,  KALOS, Michael, D. ,  HENDERSON, Robert, A. ,  MCNEILL, Patricia, D. ,  FANGER, Neil ,  RETTER, Marc, W. ,  DURHAM, Margarita ,  FANGER, Gary, Richard ,  VEDVICK, Thomas, S. ,  CARTER, Darrick ,  WATANABE, Yoshihiro ,  PECKHAM, David, W.

IPC分类号： C12N15/12 ,  C07K14/47 ,  C07K16/30 ,  G01N33/574 ,  C12Q1/68 ,  C12N5/08 ,  A61K38/17 ,  A61K31/711 ,  A61K39/395 ,  A61K35/14

CPC分类号： C07K16/3023 ,  C07K14/47 ,  C07K2317/21 ,  C07K2317/34

摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.

公开(公告)号：EP1311673A2

公开(公告)日：2003-05-21

申请号：EP01922786.7

申请日：2001-03-27

申请人： CORIXA CORPORATION

发明人： XU, Jiangchun ,  DILLON, Davin, C. ,  MITCHAM, Jennifer, L. ,  HARLOCKER, Susan, L. ,  JIANG, Yuqiu ,  KALOS, Michael, D. ,  FANGER, Gary, Richard ,  RETTER, Marc, W. ,  STOLK, John, A. ,  DAY, Craig, H. ,  VEDVICK, Thomas, S. ,  CARTER, Darrick ,  LI, Samuel, X. ,  WANG, Aijun ,  SKEIKY, Yasir, A., W. ,  HEPLER, William, T. ,  HENDERSON, Robert, A.

IPC分类号： C12N15/12 ,  C07K14/47 ,  C12N1/21 ,  C12N5/10 ,  C07K16/18 ,  G01N33/68 ,  C07K19/00 ,  C12N15/10 ,  A61K38/17 ,  A61K31/70 ,  A61K39/395 ,  A61K35/14 ,  C12Q1/68

CPC分类号： C07K14/47

摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.

公开(公告)号：EP1349870B1

公开(公告)日：2008-10-08

申请号：EP01954748.8

申请日：2001-07-17

申请人： CORIXA CORPORATION

发明人： MITCHAM, Jennifer, L. ,  KING, Gordon, E. ,  ALGATE, Paul, A. ,  FLING, Steven, P. ,  RETTER, Marc, W. ,  FANGER, Gary, Richard ,  REED, Steven, G. ,  VEDVICK, Thomas, S. ,  CARTER, Darrick ,  HILL, Paul ,  ALBONE, Earl

IPC分类号： C07K14/47 ,  C12N15/12 ,  C12N15/85 ,  C12N5/10 ,  C07K16/30 ,  G01N33/574 ,  C12Q1/68 ,  C12N15/62 ,  C12N5/06 ,  A61K39/00 ,  A61K39/395

CPC分类号： C07K14/70532 ,  A61K38/00 ,  A61K39/00 ,  A61K2039/505 ,  C07K14/47 ,  C07K14/4748 ,  C07K16/3069 ,  C07K2317/34 ,  C07K2317/77 ,  C07K2319/00 ,  C07K2319/55 ,  G01N33/57449 ,  Y02A50/472

摘要： Compositions and methods for the therapy and diagnosis of cancer, such as ovarian cancer, are disclosed. Compositions may comprise one or more ovarian carcinoma proteins, immunogenic portions thereof, polynucleotides that encode such portions or antibodies or immune system cells specific for such proteins. Such compositions may be used, for example, for the prevention and treatment of diseases such as ovarian cancer. Methods are further provided for identifying tumor antigens that are secreted from ovarian carcinomas and/or other tumors. Polypeptides and polynucleotides as provided herein may further be used for the diagnosis and monitoring of ovarian cancer.

公开(公告)号：EP1349870A2

公开(公告)日：2003-10-08

申请号：EP01954748.8

申请日：2001-07-17

申请人： CORIXA CORPORATION

发明人： MITCHAM, Jennifer, L. ,  KING, Gordon, E. ,  ALGATE, Paul, A. ,  FLING, Steven, P. ,  RETTER, Marc, W. ,  FANGER, Gary, Richard ,  REED, Steven, G. ,  VEDVICK, Thomas, S. ,  CARTER, Darrick ,  HILL, Paul ,  ALBONE, Earl

IPC分类号： C07K14/47 ,  C12N15/12 ,  C12N15/85 ,  C12N5/10 ,  C07K16/30 ,  G01N33/574 ,  C12Q1/68 ,  C12N15/62 ,  C12N5/06 ,  A61K39/00 ,  A61K39/395

CPC分类号： C07K14/70532 ,  A61K38/00 ,  A61K39/00 ,  A61K2039/505 ,  C07K14/47 ,  C07K14/4748 ,  C07K16/3069 ,  C07K2317/34 ,  C07K2317/77 ,  C07K2319/00 ,  C07K2319/55 ,  G01N33/57449 ,  Y02A50/472

摘要： Compositions and methods for the therapy and diagnosis of cancer, such as ovarian cancer, are disclosed. Compositions may comprise one or more ovarian carcinoma proteins, immunogenic portions thereof, polynucleotides that encode such portions or antibodies or immune system cells specific for such proteins. Such compositions may be used, for example, for the prevention and treatment of diseases such as ovarian cancer. Methods are further provided for identifying tumor antigens that are secreted from ovarian carcinomas and/or other tumors. Polypeptides and polynucleotides as provided herein may further be used for the diagnosis and monitoring of ovarian cancer.

公开(公告)号：EP1343886A2

公开(公告)日：2003-09-17

申请号：EP01984164.2

申请日：2001-07-10

申请人： CORIXA CORPORATION

发明人： WANG, Tongtong ,  WATANABE, Yoshihiro ,  HENDERSON, Robert, A. ,  JOHNSON, Jeffrey, C. ,  RETTER, Marc, W. ,  DURHAM,Margarita ,  CARTER, Darrick ,  FANGER, Gary, Richard ,  VEDVICK, Thomas, S. ,  BANGUR, Chaitanya, S. ,  MCNABB, Andria ,  WANG, Aijun ,  FANGER, Neil ,  SWITZER, Ann ,  MCNEILL, Patricia, D. ,  CLAPPER, Jonathan, D.

IPC分类号： C12N15/12 ,  C07K14/47 ,  C07K14/705 ,  C07K16/30 ,  G01N33/574 ,  G01N33/68 ,  C12Q1/68 ,  C12N15/62 ,  C12N5/10 ,  A61K38/17 ,  A61K48/00 ,  A61K39/395 ,  A61P35/00

CPC分类号： C07K14/47 ,  A61K38/00 ,  A61K2039/5154 ,  A61K2039/5156 ,  C07K2319/00

摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.

公开(公告)号：EP1261708A2

公开(公告)日：2002-12-04

申请号：EP01906582.0

申请日：2001-01-16

申请人： CORIXA CORPORATION

发明人： XU, Jiangchun ,  DILLON, Davin, C. ,  MITCHAM, Jennifer, L. ,  HARLOCKER, Susan, L. ,  JIANG, Yuqiu ,  REED, Steven, G. ,  KALOS, Michael, D. ,  FANGER, Gary, Richard ,  DAY, Craig, H. ,  RETTER, Marc, W. ,  STOLK, John, A. ,  SKEIKY, Yasir, A.W. ,  WANG, Aijun ,  MEAGHER, Madeleine, Joy

IPC分类号： C12N15/12 ,  C12N15/11 ,  C12N1/21 ,  C12N5/10 ,  C07K14/47 ,  C07K16/18 ,  C07K19/00 ,  A61K38/17 ,  A61K48/00 ,  G01N33/68 ,  C12Q1/68 ,  C12N5/08

CPC分类号： C07K14/005 ,  A61K39/00 ,  A61K2039/53 ,  C07K2319/00 ,  C12N9/6424 ,  C12N2760/16022

摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.

公开(公告)号：EP1185557A1

公开(公告)日：2002-03-13

申请号：EP00939407.3

申请日：2000-05-26

申请人： CORIXA CORPORATION

发明人： FANGER, Gary, Richard ,  Hendrickson, Ronald C ,  Houghton, Raymond, L. ,  REED, Steven, G.

IPC分类号： C07K14/47 ,  C12Q1/68 ,  G01N33/574

CPC分类号： G01N33/57415 ,  A61K38/00 ,  A61K39/00 ,  C07K14/4721 ,  C12Q1/6886 ,  C12Q2600/158

摘要： Compositions and methods for the therapy, diagnosis and monitoring of breast cancer are disclosed. Compositions may comprise one or more mammaglobin epitopes, or antibodies or T cells thereto, and may be used, for example, for the prevention and treatment of breast cancer. Diagnostic methods based on detecting the presence of mammaglobin epitopes, or antibodies or T cells thereto, in a sample are also provided. Also provided are methods for detecting RNA encoding mammaglobin in patient blood or fractions thereof. These methods may be used to detect and/or monitor the progression of breast cancer.