-
公开(公告)号：EP2356246A1
公开(公告)日：2011-08-17
申请号：EP08875859.4
申请日：2008-11-17
申请人： CSIR
发明人： VISSER, Daniel, Finsch , GORDON, Gregory, Ernest, Robert , HENNESSY, Fritha , RASHAMUSE, Konanani, Justice , BRADY, Dean , BODE, Moira, Leanne , LOUW, Maureen, Elizabeth
CPC分类号： C12P19/385 , C12N9/1077
摘要： A method for manipulating a nucleoside includes converting guanosine to 5- methyluridine by means of biocatalytic transglycosylation. The biocatalyst comprises a combination of a purine nucleoside phosphorylase from Bacillus halodurans, PNPase (BH1531 ) of sequence ID No 1, or a protein with at least 90% sequence similarity thereto, and a pyhmidine nucleoside phosphorylase (PyNPase).
-
公开(公告)号：EP2356246B1
公开(公告)日：2012-08-22
申请号：EP08875859.4
申请日：2008-11-17
申请人： CSIR
发明人： VISSER, Daniel, Finsch , GORDON, Gregory, Ernest, Robert , HENNESSY, Fritha , RASHAMUSE, Konanani, Justice , BRADY, Dean , BODE, Moira, Leanne , LOUW, Maureen, Elizabeth
CPC分类号： C12P19/385 , C12N9/1077
摘要： A method for manipulating a nucleoside includes converting guanosine to 5- methyluridine by means of biocatalytic transglycosylation. The biocatalyst comprises a combination of a purine nucleoside phosphorylase from Bacillus halodurans, PNPase (BH1531 ) of sequence ID No 1, or a protein with at least 90% sequence similarity thereto, and a pyhmidine nucleoside phosphorylase (PyNPase).
-
3.发明授权IMIDAZOPYRIDINES AND IMIDAZOPYRIMIDINES AS HIV-I REVERSE TRANSCRIPTASE INHIBITORS 有权咪唑并吡啶和imidazopyrimidines作为抑制剂的HIV-1逆转录酶
公开(公告)号：EP2334675B1
公开(公告)日：2014-03-26
申请号：EP09787196.6
申请日：2009-09-15
申请人： CSIR
发明人： BODE, Moira, Leanne , ROUSSEAU, Amanda, Louise , GRAVESTOCK, David , MOLEELE, Simon, Sana , VAN DER WESTHUYZEN, Christiaan, Wynand
IPC分类号： C07D471/04 , C07D487/04 , A61K31/437 , A61K31/519 , A61P31/18
CPC分类号： C07D471/04 , C07D487/04
-
4.发明公开IMIDAZOPYRIDINES AND IMIDAZOPYRIMIDINES AS HIV-I REVERSE TRANSCRIPTASE INHIBITORS 有权咪唑并吡啶和imidazopyrimidines作为抑制剂的HIV-1逆转录酶
公开(公告)号：EP2334675A1
公开(公告)日：2011-06-22
申请号：EP09787196.6
申请日：2009-09-15
申请人： CSIR
发明人： BODE, Moira, Leanne , ROUSSEAU, Amanda, Louise , GRAVESTOCK, David , MOLEELE, Simon, Sana , VAN DER WESTHUYZEN, Christiaan, Wynand
IPC分类号： C07D471/04 , C07D487/04 , A61K31/437 , A61K31/519 , A61P31/18
CPC分类号： C07D471/04 , C07D487/04
摘要： The invention provides compounds of formula A or B which are useful in the treatment of a subject infected with HIV.
-
-
-
搜索结果
4 条记录 (耗时 0.008 秒)
