专利检索 ap:("California Institute of Technology" OR "Provivi, Inc.") AND inv:"MCINTOSH, John A." 第 1 页

1.

发明公开
HEMOPROTEIN CATALYSTS FOR IMPROVED ENANTIOSELECTIVE ENZYMATIC SYNTHESIS OF TICAGRELOR 审中-公开
标题翻译：血红蛋白催化剂改进对映体选择性酶促合成甘油三酯

公开(公告)号：EP3303267A2

公开(公告)日：2018-04-11

申请号：EP16800751.6

申请日：2016-05-26

申请人： California Institute of Technology , Provivi, Inc.

发明人： ARNOLD, Frances H. , RENATA, Hans , MCINTOSH, John A. , LEWIS, Russell D. , KAN, Sek Bik Jennifer , HERNANDEZ, Kari , COELHO, Pedro , ROZZELL, David , ZHANG, Chen

IPC分类号： C07C2/52 , C07K14/795 , C07K14/80 , C07K14/805 , C12N15/31 , C12P1/04

CPC分类号： C12P7/62 , C07C49/697 , C12N9/0071 , C12P7/26 , C12Y106/02004 , C12Y114/14001 , C12Y114/15003

摘要： The present invention provides methods by which trans-(1R,2S)-2-(3,4-difluorophenyl)-cyclopropylamine and related cyclopropane compounds are prepared using synthetic strategies that include a biocatalytic cyclopropanation step.