公开(公告)号：EP1159051A1

公开(公告)日：2001-12-05

申请号：EP99968200.8

申请日：1999-12-30

申请人： Cardiovention, Inc.

发明人： DUERI, Jean-Pierre ,  JOCHIM, Robert ,  LEYNOV, Alex

IPC分类号： B01D24/28

CPC分类号： F28F21/062 ,  A61M1/1006 ,  A61M1/101 ,  A61M1/1013 ,  A61M1/1025 ,  A61M1/1029 ,  A61M1/1036 ,  A61M1/1625 ,  A61M1/1629 ,  A61M1/1698 ,  A61M1/262 ,  A61M1/267 ,  A61M2205/366

摘要： An integrated blood pump (110), oxygenator, and heat exchanger is provided having a rotating hollow fiber bundle (115) assembly. A plurality of vanes arranged along a central shaft (124) of the device increase pressure near the center of the fiber bundle (115) to develop sufficient pressure head to pump the blood through the heat exchanger. In alternative embodiments, the heat exchanger comprises a pleated metal wall, a bundle of non-permeable hollow fibers (115), or a coiled tube (130) disposed between the rotating hollow fiber bundle (115), and an interior wall of the housing (113).

公开(公告)号：EP1163035A1

公开(公告)日：2001-12-19

申请号：EP99967767.7

申请日：1999-12-30

申请人： Cardiovention, Inc.

发明人： FARHANGNIA, Mehrdad ,  LEYNOV, Alex ,  LOEFFLER, Joseph ,  PIPLANI, Alec, A. ,  POTTS, Greg ,  SKIELLER, Christian

IPC分类号： B01D24/28

CPC分类号： F28F21/062 ,  A61M1/1006 ,  A61M1/101 ,  A61M1/1013 ,  A61M1/1025 ,  A61M1/1036 ,  A61M1/1625 ,  A61M1/1629 ,  A61M1/1698 ,  A61M1/262 ,  A61M1/267 ,  A61M2205/366 ,  Y10S261/28

摘要： An integrated blood pump/oxygenator (80) having a rotating hollow fiber bundle assembly (81) that both oxygenates, and pumps blood is provided that includes a plurality of partitions (82) (84) (85) disposed within or about the fiber bundle assembly (81) to lengthen the flow path of blood (87) (88) passing through the fiber bundle (81). Alternatively, or in addition, blood flow paths (87) (88) may be lengthened, oxygenation improved by providing internal recirculation paths within the pump/oxygenator, which also advantageously may be used to reduce blood trauma caused by stagnation nearing moving parts, and heat build-up.

公开(公告)号：EP1163034A1

公开(公告)日：2001-12-19

申请号：EP99967749.5

申请日：1999-12-30

申请人： Cardiovention, Inc.

发明人： AFZAL, Thomas, A. ,  DUERI, Jean-Pierre ,  LEYNOV, Alex ,  MAKAREWICZ, Anthony ,  PIPLANI, Alec, A. ,  POTTS, Greg

IPC分类号： B01D24/28

CPC分类号： A61M1/267 ,  A61M1/1006 ,  A61M1/101 ,  A61M1/1012 ,  A61M1/1013 ,  A61M1/1025 ,  A61M1/1036 ,  A61M1/1625 ,  A61M1/1629 ,  A61M1/1698 ,  A61M1/262 ,  A61M2205/366

摘要： Improvements to integrated blood pump/oxygenator (120) having a rotating hollow fiber bundle (127) assembly that both oxygenates, and pumps blood, are provided. An inner member arranged along a central axis of the device accelerates blood entering the fiber bundle (127) to reduce micro-bubble generation, and blood trauma. Shearing loads imposed on the fiber elements of the fiber bundle (127) are reduced by the addition of a reinforcement structure, while the gas flow path is configured to reduce flooding, and loss of oxygenation efficiency due to occasional rupture of fiber elements.

摘要翻译： 提供了具有旋转中空纤维束（127）组件的集成式血泵/充氧器（120）的改进，所述组件既充氧又泵送血液。 沿着装置的中心轴布置的内部构件加速血液进入纤维束（127）以减少微气泡的产生和血液创伤。 施加在纤维束（127）的纤维元件上的剪切载荷通过添加增强结构而减小，而气体流动路径被配置为减少淹水，并且由于纤维元件偶尔破裂而导致氧化效率的损失。