摘要:
The invention relates to a peptide having the sequence (I) or (Ia), wherein X1, X2, X3, X4, X5, X7, X8, X9, X10, X11, X12, X13, X14, X15, X16 each represent an α-aminoacid, X6 representing tryptophane. Said peptide comprises between 6 and 10 hydrophobic aminoacids. The invention also relates to the use of said peptide for introducing into living cells an active molecule acting on cellular functions.
摘要:
The invention relates to a composition comprising a macromolecule or particle having one or several hydrophobic domains on the surface thereof whereby at least one transducer peptide is adsorbed thereon. Said composition can be used to introduce the macromolecule or particle into living cells.
摘要:
Nouvelle classe de facteurs de croissance cellulaires, actifs en particulier sur les cellules nerveuses, lesdits facteurs comprenant au moins un peptide homéoboîte, éventuellement lié à une autre séquence peptidique.
摘要:
The present invention relates to the use of a homeoprotein or a recombinant vector encoding said protein for treating or preventing DNA damage and/or cellular aging. In particular, the invention concerns the use of Engrailed for the treatment of amyotrophic lateral sclerosis disease.
摘要:
The invention relates to the treatment of neurodegenerative diseases, in particular Alzheimer's disease, by inhibition of the synthesis of βΑΡΡ or of the activity of the Aβ peptide in the choroid plexus.