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公开(公告)号:EP4252772A3
公开(公告)日:2023-11-01
申请号:EP23173235.5
申请日:2012-07-06
申请人: Centre National de la Recherche Scientifique (CNRS) , Azienda socio-sanitaria territoriale Papa Giovanni XXIII , Kadouche, Jean , University of Lausanne
发明人: KADOUCHE, Jean , MACH, Jean-Pierre , MICHIELIN, Olivier , ZOETE, Vincent , IWASZKIEWICZ, Justyna , CERUTTI, Martine , CHOBLET THERY, Sylvie , GOLAY, Josée
IPC分类号: C07K16/46 , A61K39/395
摘要: The invention relates to multispecific antibody constructs comprising Fab fragments having mutations at the interface of the CH1 and CL domains, said mutations preventing heavy chain/light chain mispairing.
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公开(公告)号:EP4252772A2
公开(公告)日:2023-10-04
申请号:EP23173235.5
申请日:2012-07-06
申请人: Centre National de la Recherche Scientifique (CNRS) , Azienda socio-sanitaria territoriale Papa Giovanni XXIII , Kadouche, Jean , University of Lausanne
发明人: KADOUCHE, Jean , MACH, Jean-Pierre , MICHIELIN, Olivier , ZOETE, Vincent , IWASZKIEWICZ, Justyna , CERUTTI, Martine , CHOBLET THERY, Sylvie , GOLAY, Josée
IPC分类号: A61K39/395
摘要: The invention relates to multispecific antibody constructs comprising Fab fragments having mutations at the interface of the CH1 and CL domains, said mutations preventing heavy chain/light chain mispairing.
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公开(公告)号:EP3872095A1
公开(公告)日:2021-09-01
申请号:EP20168633.4
申请日:2012-07-06
申请人: Centre National de la Recherche Scientifique (CNRS) , University of Lausanne , Azienda socio-sanitaria territoriale Papa Giovanni XXIII , Kadouche, Jean
发明人: KADOUCHE, Jean , MACH, Jean-Pierre , MICHIELIN, Olivier , ZOETE, Vincent , IWASZKIEWICZ, Justyna , CERUTTI, Martine , CHOBLET, Sylvie , GOLAY, Josée
IPC分类号: C07K16/46 , A61K39/395
摘要: The invention relates to multispecific antibody constructs comprising Fab fragments having mutations at the interface of the CH1 and CL domains, said mutations preventing heavy chain/light chain mispairing.
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公开(公告)号:EP4243852A1
公开(公告)日:2023-09-20
申请号:EP21892863.8
申请日:2021-11-12
申请人: Ludwig Institute for Cancer Research Ltd , Centre Hospitalier Universitaire Vaudois , University of Lausanne
发明人: COUKOS, George , IRVING, Melita , ZOETE, Vincent
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公开(公告)号:EP4396823A1
公开(公告)日:2024-07-10
申请号:EP22772834.2
申请日:2022-08-30
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