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1.发明授权PROCÉDÉ DE PRÉPARATION DE DÉRIVÉS (POLY(OXYDE D'ÉTHYLÈNE) POLY(OXYDE DE PROPYLÈNE)) THERMOSENSIBLES UTILES POUR FONCTIONNALISER LE CHITOSANE. 有权用于生产热敏感（聚（环氧乙烷） - 聚（环氧丙烷）） - 衍生壳聚糖的目的，功能化USED
公开(公告)号：EP2190884B1
公开(公告)日：2011-07-20
申请号：EP08804024.1
申请日：2008-09-11
IPC分类号： C08B37/00 , C08G65/333 , C08G81/00 , A61K8/73 , A61K8/91 , A61K31/722 , A61P17/02 , A61L27/20 , A61L27/52
CPC分类号： A61L27/52 , A61K8/042 , A61K8/90 , A61K31/722 , A61L27/20 , A61Q19/00 , C08B37/003 , C08G65/331 , C08G65/3324 , C08G65/333 , C08G81/00 , C08G2261/126 , C08G2650/50 , C08J3/075 , C08J2387/00 , C08L5/08 , C08L71/02 , C08L3/00
摘要： The invention relates to a thermosensitive (poly(ethylene oxide) poly(propylene oxide))-acetal derivative, which can be used to functionalize chitosan, and to the process for the preparation thereof. The invention therefore also relates to a process for functionalizing chitosan by grafting this thermosensitive copolymer and optionally another thermosensitive polymer, poly(ethylene oxide). A subject of the invention is also a chitosan-(poly(ethylene oxide) poly(propylene oxide))-poly(ethylene oxide) derivative which has the advantage of being water-soluble at physiological pH. The invention therefore also relates to the aqueous compositions comprising this derivative and to the use of this composition for the manufacture of gel by heating.
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2.发明公开PROCÉDÉ DE PRÉPARATION DE DÉRIVÉS (POLY(OXYDE D'ÉTHYLÈNE) POLY(OXYDE DE PROPYLÈNE)) THERMOSENSIBLES UTILES POUR FONCTIONNALISER LE CHITOSANE. 有权用于生产热敏感（聚（环氧乙烷） - 聚（环氧丙烷）） - 衍生壳聚糖的目的，功能化USED
公开(公告)号：EP2190884A1
公开(公告)日：2010-06-02
申请号：EP08804024.1
申请日：2008-09-11
IPC分类号： C08B37/00 , C08G65/333 , C08G81/00 , A61K8/73 , A61K8/91 , A61K31/722 , A61P17/02 , A61L27/20 , A61L27/52
CPC分类号： A61L27/52 , A61K8/042 , A61K8/90 , A61K31/722 , A61L27/20 , A61Q19/00 , C08B37/003 , C08G65/331 , C08G65/3324 , C08G65/333 , C08G81/00 , C08G2261/126 , C08G2650/50 , C08J3/075 , C08J2387/00 , C08L5/08 , C08L71/02 , C08L3/00
摘要： The invention relates to a thermosensitive (poly(ethylene oxide) poly(propylene oxide))-acetal derivative, which can be used to functionalize chitosan, and to the process for the preparation thereof. The invention therefore also relates to a process for functionalizing chitosan by grafting this thermosensitive copolymer and optionally another thermosensitive polymer, poly(ethylene oxide). A subject of the invention is also a chitosan-(poly(ethylene oxide) poly(propylene oxide))-poly(ethylene oxide) derivative which has the advantage of being water-soluble at physiological pH. The invention therefore also relates to the aqueous compositions comprising this derivative and to the use of this composition for the manufacture of gel by heating.
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