公开(公告)号：EP2714930B1

公开(公告)日：2017-02-01

申请号：EP12729671.3

申请日：2012-05-25

申请人： Universite Joseph Fourier (Grenoble 1) ,  Centre National de la Recherche Scientifique

发明人： TABERLET, Pierre ,  COISSAC, Eric ,  RIAZ, Tiayyba

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6888

公开(公告)号：EP2417151B1

公开(公告)日：2016-09-14

申请号：EP10723209.2

申请日：2010-04-06

申请人： Universite Joseph Fourier (Grenoble 1) ,  Centre National de la Recherche Scientifique ,  INSERM - Institut National de la Santé et de la Recherche Médicale

发明人： WONG, Yung-Sing ,  HAKIMI, Mohamed-Ali ,  BOUGDOUR, Alexandre ,  PELLOUX, Hervé ,  MAUBON, Danièle

IPC分类号： C07K5/12 ,  A61P33/02 ,  A61P33/06 ,  A61P33/00 ,  A61K38/12

CPC分类号： C07K5/126 ,  A61K38/00 ,  A61K38/07 ,  A61K38/12 ,  C07K1/107 ,  C07K1/1075 ,  C07K1/1077 ,  C07K5/12 ,  Y02A50/411

公开(公告)号：EP2680876B1

公开(公告)日：2015-11-04

申请号：EP12712302.4

申请日：2012-02-29

申请人： Universite Joseph Fourier (Grenoble 1) ,  Centre National de la Recherche Scientifique

发明人： POLACK, Benoît ,  THOMAS, Aline

IPC分类号： A61K38/48 ,  C07K14/745 ,  A61P7/04

CPC分类号： C12N9/6432 ,  A61K38/4846 ,  C12Y304/21006

公开(公告)号：EP2306911B1

公开(公告)日：2015-01-28

申请号：EP09781211.9

申请日：2009-07-28

申请人： Universite Joseph Fourier - Grenoble 1

发明人： CINQUIN, Philippe ,  AVILA VILCHIS, Juan, Carlos ,  ZEMITI, Nabil ,  VILCHIS GONZALEZ, Adriana, Herlinda

IPC分类号： A61B17/28 ,  A61B17/00 ,  A61B19/00

CPC分类号： A61B17/29 ,  A61B17/00234 ,  A61B34/30 ,  A61B2017/00265 ,  A61B2017/00477 ,  A61B2017/00544 ,  A61B2017/2931 ,  Y10T29/49826

公开(公告)号：EP2785858A1

公开(公告)日：2014-10-08

申请号：EP12806590.1

申请日：2012-11-28

申请人： Universite Joseph Fourier (Grenoble 1) ,  Centre Hospitalier Universitaire de Grenoble

发明人： DROUET, Christian ,  GHANNAM, Arije ,  DEFENDI, Federica ,  FAVIER, Bertrand

IPC分类号： C12Q1/37

CPC分类号： C12Q1/37

摘要： The present invention relates to a method for dosing the control capacity of plasma serpin (SERine Protease INhibitor) C1 inhibitor (C1Inh) on the basis of a patient blood sample. The invention also relates to a kit specially designed for said dosing.

公开(公告)号：EP2680876A1

公开(公告)日：2014-01-08

申请号：EP12712302.4

申请日：2012-02-29

申请人： Universite Joseph Fourier (Grenoble 1) ,  Centre National de la Recherche Scientifique

发明人： POLACK, Benoît ,  THOMAS, Aline

IPC分类号： A61K38/36 ,  C07K14/745 ,  A61P7/04

CPC分类号： C12N9/6432 ,  A61K38/4846 ,  C12Y304/21006

摘要： The invention relates to a pharmaceutical composition comprising a modified Xa factor (GDXa), said modified GDXa being non-thrombogenic and able to bind to the TFPI but not to the phospholipids, for preventing or treating a hemorrhagic accident in a patient suffering from haemophilia A or B with or without inhibitor.

公开(公告)号：EP2453888A1

公开(公告)日：2012-05-23

申请号：EP10752018.1

申请日：2010-07-15

申请人： Universite Joseph Fourier (Grenoble 1) ,  CNRS Centre National de la Recherche Scientifique

发明人： DE LORGERIL, Michel ,  SALEN, Patricia

IPC分类号： A61K31/202 ,  A61K31/352 ,  A61K31/353 ,  A61K45/06

CPC分类号： A23K20/158 ,  A23K20/111 ,  A23K20/121 ,  A23L33/105 ,  A23L33/12 ,  A23V2002/00 ,  A61K31/202 ,  A61K31/352 ,  A61K31/353 ,  A61K45/06 ,  A61K2300/00 ,  A23V2250/1882 ,  A23V2250/2132

摘要： The present invention relates to the use of at least one fatty acid of the omega-3 group, selected from among α-linolenic acid and stearidonic acid, and of at least one polyphenol as an agent for increasing the endogenous synthesis of eicosapentanoic acid and docosahexanoic acid, for preparing a food, health, or pharmaceutical composition to be administered to a human being or to an animal.

公开(公告)号：EP1928918B1

公开(公告)日：2011-11-16

申请号：EP05798990.7

申请日：2005-09-27

申请人： UNIVERSITE JOSEPH FOURIER - Grenoble 1 ,  Ben-Gurion University of the Negev Research and Development Authority

发明人： MARKS, Robert ,  COSNIER, Serge ,  ABU-RABEAH, Khalil ,  IONESCU, Elena Rodica ,  POLYAK, Boris

IPC分类号： C08B37/00

CPC分类号： C08B37/00 ,  C08B37/003 ,  C08B37/0042 ,  C08B37/0072 ,  C08B37/0084 ,  C08L5/04

摘要： The present invention relates to a new hydrogel functionalized with a polymerizable moiety, the polymerized hydrogels, films and gels comprising the same and their use for cells, proteins, DNA or other molecules encapsulation, including use as biosensors or bioreactors.

公开(公告)号：EP2378968A1

公开(公告)日：2011-10-26

申请号：EP09755901.7

申请日：2009-11-18

申请人： Universite Joseph Fourier - Grenoble 1 ,  Centre National de la Recherche Scientifique - CNRS ,  Informatique De Securite

发明人： VUILLERME, Nicolas ,  PAYAN, Yohan ,  CHENU, Olivier ,  DIOT, Bruno ,  CANNARD, Francis ,  LAVARENNE, Christophe

IPC分类号： A61B5/103

CPC分类号： A61B5/445 ,  A61B5/0053 ,  A61B5/444 ,  A61B5/447 ,  A61B5/7275 ,  A61G7/057 ,  A61G2203/34 ,  G06F19/00

摘要： The invention relates to a device for preventing the occurrence of eschars in a patient, that includes: means for acquiring at least one so-called physiological signal representative of eschar occurrence in a patient, such as a pressure in at least one bearing area of the patient; means for transmitting said signal to a processing system; a processing system capable, from the transmitted signals, of determining a risk level of eschar occurrence; means for determining a customised warning level; means for comparing said determined risk level with said customised warning level; and means for initiating a warning if said risk level is higher than said warning level.

公开(公告)号：EP2229665A1

公开(公告)日：2010-09-22

申请号：EP08856967.8

申请日：2008-12-03

申请人： Vigilio ,  Universite Joseph Fourier - Grenoble 1

发明人： NOURY, Norbert ,  LUNDY, Jean-Eric

IPC分类号： G08B21/04 ,  A61B5/00 ,  G06F19/00

CPC分类号： A61B5/7282 ,  A61B5/0002 ,  A61B5/01 ,  A61B5/02055 ,  A61B5/02405 ,  A61B5/076 ,  A61B5/0816 ,  A61B5/1117 ,  A61B5/1118 ,  A61B5/14532 ,  A61B5/7246 ,  A61B5/7264 ,  A61B5/7275 ,  A61B5/7405 ,  A61B5/746 ,  G06F19/00 ,  G08B21/0446 ,  G08B21/0453 ,  G16H50/20

摘要： The invention relates to a method for detecting the critical situation of a subject that comprises measuring a physiological parameter of said subject. The method is characterised in that it comprises the following steps: (a) measuring the physiological parameter; (b) calculating a variation rate of the physiological parameter; (c) determining a synthesis variable for the physiological parameter by taking into account both the value of the parameter and the variation rate thereof; and (d) detecting a critical situation (25) from said synthesis variable. Advantageously, the steps (a) to (c) are implemented for at least two physiological parameters, and the method further includes determining a global decision variable (23) from the different synthesis variables, the critical situation being detected during step (d) from said global decision variable. The invention can be used for improving the detection of accidents or health problems particularly for the elderly at their places of residence.