专利检索 ap:("Chirotech Technology Limited") AND inv:"McCAGUE, Raymond" 第 1 页

1.

发明授权
PROCESS FOR THE PREPARATION OF GALANTHAMINE AND ITS DERIVATIVES 失效
标题翻译：用于生产加兰他敏及其衍生物

公开(公告)号：EP0853624B1

公开(公告)日：2001-02-14

申请号：EP96931170.3

申请日：1996-09-23

申请人： Chirotech Technology Limited

发明人： BANNISTER, Robin, Mark, Chiroscience Limited , McCAGUE, Raymond

IPC分类号： C07D491/10 , C12P17/18

CPC分类号： C07D491/10 , C12P17/18

摘要： A process for preparing a compound having a formula (4) or (5), in either optically-enriched or racemic form, wherein R?1, R2, R3 and R4¿ are independently selected from hydrogen, alkyl, aryl, alkaryl, aralkyl and acyl groups, comprises mixing with a plant extract an oxidative cyclisation precursor of the said compound.

2.

发明授权
CHIRAL CYCLOPENTENE DERIVATIVES AND THEIR PREPARATION 失效
标题翻译：手性环戊烯和生产

公开(公告)号：EP0638077B1

公开(公告)日：2001-09-19

申请号：EP93909073.4

申请日：1993-04-21

申请人： Chirotech Technology Limited

发明人： ROBERTS, Stanley Michael , OLIVO, Horacio F. , McCAGUE, Raymond

IPC分类号： C07D307/93 , C12P41/00 , C12P17/04 , C07C35/06

CPC分类号： C07D307/935 , C07C35/06 , C12P17/04 , C12P41/004

摘要： An optically-purified enantiomer of the lactone 4-hydroxy-2-oxabicyclo-[3.3.0]oct-7-en-3-one or an acylate thereof can be obtained by biotransformation. It is a useful synthon in the preparation of an enantiomer of 3-hydroxymethyl-2-hydroxycyclopentene that can be used to prepare carbocyclic nucleosides as a desired enantiomer.

3.

发明授权
CYCLOALKANEDIOLS AND THEIR USE IN PREPARING CHIRAL COMPOUNDS 失效
标题翻译： CYCLOALKANEDIOLE及其用途用于生产手性化合物

公开(公告)号：EP0722437B1

公开(公告)日：1999-08-25

申请号：EP94928493.9

申请日：1994-10-07

申请人： Chirotech Technology Limited

发明人： McCAGUE, Raymond , RUECROFT, Graham , PALMER, Christopher

IPC分类号： C07C271/24 , C07D317/44

CPC分类号： C07C271/24 , C07C237/24 , C07C2601/08 , C07D317/44 , C08G73/0206 , D06M13/432 , D06M15/564 , D06M15/59 , D06M15/61 , D06M16/00

摘要： A process for the product of a 2,3-cis-dihydroxycycloalkane-1-carboxamide, comprises dihydroxylation of the corresponding cycloalkene-1-carboxamide. Some products are new. The stereoselective dihydroxylation is surprising.

摘要翻译： PCT号 PCT / GB94 / 02194秒。 371日期1996年6月4日二段。 102（e）中的日期1996年6月4日提交的PCT十月 7，1994年PCT公开号 WO95 / 09839的PCT公布。四月13日，为2,3-顺式 - dihydroxycycloalkane -1-羧酰胺，的产品1995年a方法包括相应的环烯烃-1-羧酰胺的二羟基化。有些产品是新的。立体选择性二羟基化是令人惊讶的。

4.

发明授权
A METHOD FOR PREPARING TERT-LEUCINE AND ANALOGUES THEREOF IN ENANTIOMERIC FORM, AND INTERMEDIATES THEREIN 失效
标题翻译：用于生产TERT亮氨酸和ANALOG IN ENANTIEMERER FORM和中间产品

公开(公告)号：EP0726891B1

公开(公告)日：1999-02-03

申请号：EP94931136.9

申请日：1994-11-01

申请人： Chirotech Technology Limited

发明人： TURNER, Nicholas , WINTERMAN, James , McCAGUE, Raymond

IPC分类号： C07C233/83 , C12P41/00 , C07D263/42 , C07D263/44

CPC分类号： C07D263/44 , C07C233/83 , C07D263/42 , C12P41/003

摘要： A novel azlactone of formula (3), or the opposite enatiomer, wherein R?1, R2, R3¿ and X are each a substituent, undergoes biotransformation, using suitable enzymatic activity, in the presence of a base YH to form an N-acyl-amino-acid of formula (2), wherein Y is a group derivable from the base YH and convertable to OH. An amino-acid of formula (1), or the opposite enantiomer, can be prepared in high e.e. from a compound of formula (2) by converting Y to OH.