摘要:
Trocart (1) comportant une paroi périphérique (2) s'étendant selon un axe longitudinal (z), dont la section, dans un plan perpendiculaire audit axe longitudinal, est inscrite dans un premier cercle d'un premier diamètre, de sorte que le trocart est apte à coulisser à l'intérieur d'un cathéter comportant une paroi interne (3) présentant un deuxième diamètre (D) supérieur ou sensiblement égal audit premier diamètre, le périmètre de ladite section présentant au moins une inflexion (5), de sorte que, lorsque le trocart coulisse dans le cathéter, au moins un espace (7) entre le cathéter et le trocart à l'emplacement de cette inflexion reste libre.
摘要:
The invention relates to a system for delivering a liquid, comprising: - a peristaltic pump (1) operating in cycles so that an elementary volume of liquid is delivered into the pipe during the course of each cycle, - at least one actuator (51 1 , 51 2 , 51 3 ) able to cause the pump to deliver a volume of liquid, during the course of a cycle, - a control circuit (55, 56, 58, 62), for applying a control signal to the actuator so that the volume delivered during the course of a cycle is dependent on this signal applied to the actuator, - a sensor (54, 60), able to produce a signal indicative of the quantity of liquid ejected during the course of a cycle, - the control circuit (55, 56, 58, 62) being able to determine a control signal on the basis of said signal from the sensor and of a reference signal (V D , V S ).
摘要:
The invention relates to a device for transiently contacting at least one unit for capturing biological targets with a body fluid containing them, a method for recovering the captured targets for analysis, and a system for contacting and recovering a capture substrate included in said unit. The invention relates to samples obtained in particular in vivo from body fluids of the human body, e.g. circulating body fluids, said fluids possibly containing, as targets, proteins, oligonucleotides such as RNA or DNA, antibodies, enzymes or cells. A contacting device (1) according to the invention comprises: —a sampling tip (2) having a contacting end intended to be introduced into a medium containing said fluid, and—the or each capturing unit which is bound to said end and which comprises a capture substrate (3) defining a target capturing surface covered with at least one biocompatible and porous crosslinked polymer layer (4) designed to retain the or each capture substrate and only to allow biological particles including targets smaller than a limiting size to pass through, in such a way that the or each capture substrate is recoverable after said contacting by dissolution of the or each layer.
摘要:
The invention describes a system for injecting and controlling a flow of liquid to be injected, comprising: - a peristaltic pump (4); - a catheter (8) for delivering the fluid to be injected; - a pressure sensor (6) for measuring the liquid pressure in the catheter, - control means (44) for receiving data from the pressure sensor (6) and for controlling the pump (4) on the basis of the data measured at different times.
摘要:
The invention relates to a device for transiently contacting at least one unit for capturing biological targets with a body fluid containing them, a method for recovering the captured targets for analysis, and a system for contacting and recovering a capture substrate included in said unit. The invention relates to samples obtained in particular in vivo from body fluids of the human body, e.g. circulating body fluids, said fluids possibly containing, as targets, proteins, oligonucleotides such as RNA or DNA, antibodies, enzymes or cells. A contacting device (1) according to the invention comprises: —a sampling tip (2) having a contacting end intended to be introduced into a medium containing said fluid, and—the or each capturing unit which is bound to said end and which comprises a capture substrate (3) defining a target capturing surface covered with at least one biocompatible and porous crosslinked polymer layer (4) designed to retain the or each capture substrate and only to allow biological particles including targets smaller than a limiting size to pass through, in such a way that the or each capture substrate is recoverable after said contacting by dissolution of the or each layer.