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公开(公告)号:EP3952910A1
公开(公告)日:2022-02-16
申请号:EP20717633.0
申请日:2020-04-06
发明人: RÖSE, Lars , GRITZAN, Uwe , LIANG, Spencer , POW, Andrew , HUNTER, John , LEVY, Ofer , VAKNIN, Ilan
IPC分类号: A61K39/395 , A61P35/00 , C07K16/28 , A61P37/06
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2.ANTI-VSTM5 ANTIBODIES AND THE USE THEREOF IN THERAPY AND DIAGNOSIS 审中-公开
标题翻译: ANTI-VSTM5抗体和它们的用途在治疗和诊断公开(公告)号:EP3043819A1
公开(公告)日:2016-07-20
申请号:EP14844096.9
申请日:2014-09-11
申请人: Compugen Ltd.
发明人: LEVINE, Zurit , ROTMAN, Galit , DASSA, Liat , LEVY, Ofer , COJOCARU, Gad S. , TOPORIK, Amir , KLIGER, Yossef , POW, Andrew , LIANG, Spencer
IPC分类号: A61K39/395 , C07K16/18 , G01N33/574 , C07K16/30 , G01N33/564 , G01N33/569
CPC分类号: C07K16/28 , A61K31/664 , A61K38/00 , A61K39/0011 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , A61K2039/5154 , C07K14/705 , C07K16/2803 , C07K16/2818 , C07K16/30 , C07K2317/21 , C07K2317/33 , C07K2317/51 , C07K2317/515 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C07K2319/30 , G01N33/564 , G01N33/57492 , G01N2800/24 , G01N2800/26 , G01N2800/50 , G01N2800/52 , G01N2800/54 , G01N2800/56 , Y02A50/41 , Y02A50/412 , Y02A50/416 , Y02A50/421 , Y02A50/466 , Y02A50/491 , Y02A50/492 , Y02A50/55 , Y02A50/58 , A61K31/675 , A61K2039/5152 , A61K38/1774
摘要: The present invention relates to VSTM5-specific antibodies, antibody fragments, and VSTM5 polypeptides, conjugates and compositions comprising same, for modulating (antagonizing or agonizing) one or more of the effects of VSTM5 expression on immunity. More specifically, the present invention relates to VSTM5-specific antibodies, antibody fragments, and VSTM5 polypeptides, conjugates and compositions comprising same for treating and aiding in the diagnosis of cancer, infectious diseases and immune related diseases, e.g., those associated with aberrant (higher or lower than normal) VSTM5 expression by diseased and/or immune cells and/or aberrant (increased or reduced) VSTM5-mediated effects on immunity.
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公开(公告)号:EP2744830A1
公开(公告)日:2014-06-25
申请号:EP13806165.0
申请日:2013-06-19
申请人: Compugen Ltd.
发明人: COJOCARU, Gady S. , DASSA, Liat , ROTMAN, Galit , LEVY, Ofer , POW, Andrew , SAMEACH-GREENWALD, Shirley , LEVINE, Zurit
IPC分类号: C07K16/28 , A61K39/395 , A61P35/00 , A61P37/04
CPC分类号: A61K31/675 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/507 , C07K14/70503 , C07K16/28 , C07K16/2818 , C07K16/2878 , C07K16/30 , C07K2317/21 , C07K2317/34 , C07K2317/55 , C07K2317/734 , C07K2319/30 , C12N15/1138 , C12N2310/14 , G01N33/57492 , G01N2800/24 , G01N2800/26 , Y02A50/412 , Y02A50/423 , A61K2300/00
摘要: This invention relates to antibodies and antigen binding fragments and conjugates containing same, and/or alternative scaffolds, specific for LSR molecules, which are suitable drugs for immunotherapy and treatment of specific cancer.
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公开(公告)号:EP3717007A1
公开(公告)日:2020-10-07
申请号:EP18811506.7
申请日:2018-11-28
发明人: RÖSE, Lars , GRITZAN, Uwe , HÜTTER, Julia , LIANG, Spencer , POW, Andrew , HUNTER, John , LEVY, Ofer , VAKNIN, Ilan
IPC分类号: A61K39/395 , A61K31/337 , C07K16/28 , A61P37/04 , A61P35/00
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公开(公告)号:EP3971211A1
公开(公告)日:2022-03-23
申请号:EP21188908.4
申请日:2016-07-13
申请人: Compugen Ltd.
发明人: DICKEN, Yosef , DASSA, Liat , NOVIK, Amit , TOPORIK, Amir , COJOCARU, Gad S. , KLIGER, Yossef , BENITA, Yair , LEVY, Ofer , VAKNIN, Ilan , MACHLENKIN, Arthur , HECHT, Iris , KIM, Jungmin , POW, Andrew , DRAKE, Andrew W.
IPC分类号: C07K16/28 , A61K39/395 , A61P35/00
摘要: According to at least some embodiments of the present invention is directed to anti-HIDE1 antibodies and polypeptides and methods of using same.
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公开(公告)号:EP3322733A1
公开(公告)日:2018-05-23
申请号:EP16751633.5
申请日:2016-07-13
申请人: Compugen Ltd.
发明人: DICKEN, Yosef , DASSA, Liat , NOVIK, Amit , TOPORIK, Amir , COJOCARU, Gad, S. , KLIGER, Yossef , BENITA, Yair , LEVY, Ofer , VAKNIN, Ilan , MACHLENKIN, Arthur , HECHT, Iris , KIM, Jungmin , POW, Andrew , DRAKE, Andrew, W.
IPC分类号: C07K16/28 , A61K39/395 , A61P35/00
CPC分类号: C07K16/2803 , A61K31/513 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/572 , A61P35/00 , C07K14/70503 , C07K2317/524 , C07K2317/526 , C07K2317/53 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/732 , C07K2317/734 , C07K2317/92 , C07K2317/94 , C07K2319/30
摘要: According to at least some embodiments of the present invention is directed to anti-HIDE1 antibodies and polypeptides and methods of using same.
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