公开(公告)号：EP2966066B1

公开(公告)日：2018-02-14

申请号：EP14760605.7

申请日：2014-03-04

申请人： Consejo Superior De Investigaciones Científicas (CSIC) ,  Consorcio Centro de Investigación Biomédica en Red M.P. ,  Universitat Autónoma De Barcelona (UAB)

发明人： MARCO COLÁS, María Pilar ,  PASCUAL DURÁN, Nuria ,  PASTELLS DÍEZ, Carme ,  SANCHEZ BAEZA, Francisco ,  VILLAVERDE CORRALES, Antonio Pedro ,  RODRÍGUEZ CARMONA, Escarlata

IPC分类号： C07D241/46 ,  C07K16/12 ,  G01N33/569

CPC分类号： G01N33/5308 ,  C07D241/46 ,  C07K16/44 ,  C07K19/00 ,  G01N33/56911 ,  G01N2333/21 ,  G01N2469/10

摘要： The invention relates to a compound of general formula (I) and to the use thereof as a haptene. The invention also relates to a conjugate of said compound I with a carrier protein or fragment thereof, with a detectable marking agent, or with a polymer or support, and to the use thereof for producing antibodies. The invention also relates to a method for the detection and/or quantification of 1-hydroxyphenazine and/or pyocyanin using said antibodies and conjugates for the detection of infections caused by Pseudomonas aeruginosa.

公开(公告)号：EP2966066A1

公开(公告)日：2016-01-13

申请号：EP14760605.7

申请日：2014-03-04

申请人： Consejo Superior De Investigaciones Científicas (CSIC) ,  Centro de Investigación Biomédica en Red (CIBER) ,  Universidad Autónoma De Barcelona (UAB)

发明人： MARCO COLÁS, María Pilar ,  PASCUAL DURÁN, Nuria ,  PASTELLS DÍEZ, Carme ,  SANCHEZ BAEZA, Francisco ,  VILLAVERDE CORRALES, Antonio Pedro ,  RODRÍGUEZ CARMONA, Escarlata

IPC分类号： C07D241/46 ,  C07K16/12 ,  G01N33/569

CPC分类号： G01N33/5308 ,  C07D241/46 ,  C07K16/44 ,  C07K19/00 ,  G01N33/56911 ,  G01N2333/21 ,  G01N2469/10

摘要： The invention relates to a compound of general formula (I) and to the use thereof as a haptene.

The invention also relates to a conjugate of said compound I with a carrier protein or fragment thereof, with a detectable marking agent, or with a polymer or support, and to the use thereof for producing antibodies. The invention also relates to a method for the detection and/or quantification of 1-hydroxyphenazine and/or pyocyanin using said antibodies and conjugates for the detection of infections caused by Pseudomonas aeruginosa.

摘要翻译： 本发明涉及通式（I）的化合物和涉及其作为半抗原。 因此，本发明涉及与载体蛋白或其片段，所述化合物I的共轭物，用可检测的标记剂，或者与聚合物或支撑，和它们的用途用于产生抗体。 因此本发明涉及一种用于一hydroxyphenazine的检测和/或定量和/或使用绿脓菌素所述抗体和缀合物用于检测由铜绿假单胞菌引起的感染的方法。