公开(公告)号：EP2277892A3

公开(公告)日：2011-04-27

申请号：EP10179022.8

申请日：1999-12-08

申请人： Corixa Corporation

发明人： Probst, Peter ,  Bhatia, Ajay ,  Skeiky, Yasir A. W. ,  Fling, Steven P. ,  Jen, Shyian ,  Stromberg, Erica Jean

IPC分类号： C07K14/295 ,  C07K19/00 ,  C12N15/62 ,  A61K39/118

CPC分类号： C07K14/295 ,  A61K39/00 ,  A61K2039/51 ,  C07K2319/00

摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.

公开(公告)号：EP2223935A3

公开(公告)日：2010-11-24

申请号：EP10163839.3

申请日：1999-12-08

申请人： Corixa Corporation

发明人： Probst, Peter ,  Bhatia, Ajay ,  Skeiky, Yasir A. W. ,  Fling, Steven P. ,  Jen, Shyian ,  Stromberg, Erica Jean

IPC分类号： C07K14/295 ,  C07K19/00 ,  C12N15/62 ,  A61K39/118

CPC分类号： C07K14/295 ,  A61K39/00 ,  A61K2039/51 ,  C07K2319/00

摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.

公开(公告)号：EP2277893A3

公开(公告)日：2011-03-30

申请号：EP10179569.8

申请日：1999-12-08

申请人： Corixa Corporation

发明人： Probst, Peter ,  Bhatia, Ajay ,  Skeiky, Yasir A. W. ,  Fling, Steven P. ,  Jen, Shyian ,  Stromberg, Erica Jean

IPC分类号： C07K14/295 ,  C07K19/00 ,  C12N15/62 ,  A61K39/118

CPC分类号： C07K14/295 ,  A61K39/00 ,  A61K2039/51 ,  C07K2319/00

摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.

公开(公告)号：EP2277892A2

公开(公告)日：2011-01-26

申请号：EP10179022.8

申请日：1999-12-08

申请人： Corixa Corporation

发明人： Probst, Peter ,  Bhatia, Ajay ,  Skeiky, Yasir A. W. ,  Fling, Steven P. ,  Jen, Shyian ,  Stromberg, Erica Jean

IPC分类号： C07K14/295 ,  C07K19/00 ,  C12N15/62 ,  A61K39/118

CPC分类号： C07K14/295 ,  A61K39/00 ,  A61K2039/51 ,  C07K2319/00

摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.

公开(公告)号：EP2248900A1

公开(公告)日：2010-11-10

申请号：EP10174425.8

申请日：1998-05-20

申请人： CORIXA CORPORATION

发明人： Alderson, Mark ,  Dillon, Davin ,  Skeiky, Yasir A. W. ,  Campos-Neto, Antonio

IPC分类号： C12N15/31 ,  C07K14/35 ,  A61K39/04 ,  A61K48/00 ,  A61K49/00 ,  C12N15/62 ,  C07K19/00 ,  G01N33/50 ,  G01N33/60 ,  G01N33/569 ,  C12N1/19 ,  C12N1/20 ,  C12N1/21 ,  C12N5/10

CPC分类号： C07K14/35 ,  A61K38/00 ,  A61K39/00 ,  C07K2319/00

摘要： Compounds and methods for inducing protective immunity against tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one immunogenic portion of one or more M . Tuberculosis proteins and DNA molecules encoding such polypeptides. Such compounds may be formulated into vaccines and/or pharmaceutical compositions for immunization against M . Tuberculosis infection, or may be used for the diagnosis of tuberculosis.

摘要翻译： 抗结核诱导保护性免疫化合物和方法可以游离缺失盘。 所提供的化合物包括多肽也含有一种或多种M的至少一个免疫原性部分 杆菌蛋白和编码检测所述多肽的DNA分子。 搜索化合物可以配制成疫苗和/或药物组合物用于对抗M.免疫 杆菌感染，或可用于结核病的诊断。

公开(公告)号：EP2248900B1

公开(公告)日：2012-07-18

申请号：EP10174425.8

申请日：1998-05-20

申请人： CORIXA CORPORATION

发明人： Alderson, Mark ,  Dillon, Davin ,  Skeiky, Yasir A. W. ,  Campos-Neto, Antonio

IPC分类号： C12N15/31 ,  C07K14/35 ,  A61K39/04 ,  A61K48/00 ,  A61K49/00 ,  C12N15/62 ,  C07K19/00 ,  G01N33/50 ,  G01N33/60 ,  G01N33/569 ,  C12N1/19 ,  C12N1/20 ,  C12N1/21 ,  C12N5/10

CPC分类号： C07K14/35 ,  A61K38/00 ,  A61K39/00 ,  C07K2319/00

公开(公告)号：EP2223935A2

公开(公告)日：2010-09-01

申请号：EP10163839.3

申请日：1999-12-08

申请人： Corixa Corporation

发明人： Probst, Peter ,  Bhatia, Ajay ,  Skeiky, Yasir A. W. ,  Fling, Steven P. ,  Jen, Shyian ,  Stromberg, Erica Jean

IPC分类号： C07K14/295 ,  C07K19/00 ,  C12N15/62 ,  A61K39/118

CPC分类号： C07K14/295 ,  A61K39/00 ,  A61K2039/51 ,  C07K2319/00

摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.

摘要翻译： 公开了用于诊断和治疗衣原体感染的化合物和方法。 提供的化合物包括含有衣原体抗原的至少一个抗原部分的多肽和编码这些多肽的DNA序列。 还提供了包含此类多肽或DNA序列的药物组合物和疫苗以及针对这些多肽的抗体。 含有此类多肽或DNA序列的诊断试剂盒和合适的检测试剂可用于检测患者和生物样品中的衣原体感染。

公开(公告)号：EP2218733A1

公开(公告)日：2010-08-18

申请号：EP10163838.5

申请日：1999-12-08

申请人： Corixa Corporation

发明人： Probst, Peter ,  Bhatia, Ajay ,  Skeiky, Yasir A. W. ,  Fling, Steven ,  Jen, Shyian ,  Stromberg, Erica Jean

IPC分类号： C07K14/295 ,  C07K19/00 ,  C12N15/62 ,  A61K39/118

CPC分类号： C07K14/295 ,  A61K39/00 ,  A61K2039/51 ,  C07K2319/00

摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.

摘要翻译： 披露了用于诊断和治疗衣原体感染的化合物和方法。 提供的化合物包括含有衣原体抗原的至少一个抗原部分的多肽和编码这些多肽的DNA序列。 还提供了包含此类多肽或DNA序列的药物组合物和疫苗以及针对这些多肽的抗体。 含有此类多肽或DNA序列的诊断试剂盒和合适的检测试剂可用于检测患者和生物样品中的衣原体感染。

公开(公告)号：EP2270170B1

公开(公告)日：2013-11-06

申请号：EP10174426.6

申请日：1998-05-20

申请人： CORIXA CORPORATION

发明人： Alderson, Mark ,  Dillon, Davin ,  Skeiky, Yasir A. W. ,  Campos-Neto, Antonio

IPC分类号： C12N15/31 ,  C07K14/35 ,  A61K39/04 ,  C12N15/62 ,  C07K19/00 ,  G01N33/569 ,  A61K38/00 ,  A61K39/00

CPC分类号： C07K14/35 ,  A61K38/00 ,  A61K39/00 ,  C07K2319/00

公开(公告)号：EP2277893A2

公开(公告)日：2011-01-26

申请号：EP10179569.8

申请日：1999-12-08

申请人： Corixa Corporation

发明人： Probst, Peter ,  Bhatia, Ajay ,  Skeiky, Yasir A. W. ,  Fling, Steven P. ,  Jen, Shyian ,  Stromberg, Erica Jean

IPC分类号： C07K14/295 ,  C07K19/00 ,  C12N15/62 ,  A61K39/118

CPC分类号： C07K14/295 ,  A61K39/00 ,  A61K2039/51 ,  C07K2319/00

摘要： Compounds and methods for the diagnosis and treatment of Chlamydial infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a Chlamydia antigen and DNA sequences encoding such polypeptides. Pharmaceutical compositions and vaccines comprising such polypeptides or DNA sequences are also provided, together with antibodies directed against such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of Chlamydial infection in patients and in biological samples.