公开(公告)号：EP1539806A2

公开(公告)日：2005-06-15

申请号：EP02741692.4

申请日：2002-05-02

申请人： Curagen Corporation

发明人： ALSOBROOK, John P. II ,  ANDERSON, David W. ,  BOLDOG, Ferenc L. ,  BURGESS, Catherine E. ,  CASMAN, Stacie J. ,  EDINGER, Schlomit R. ,  ELLERMAN, Karen ,  GANGOLLI, Esha A. ,  GERLACH, Valerie L. ,  GORMAN, Linda ,  GUNTHER, Erik ,  HERRMANN, John L. ,  JI, Weizhen ,  LEPLEY, Denise M. ,  LEWIN, David A. ,  LI, Li ,  MACDOUGALL, John R. ,  MALYANKAR, Uriel M. ,  MEZES, Peter D. ,  PADIGARU, Muralidhara ,  PATTURAJAN, Meera ,  PEYMAN, John A. ,  RASTELLI, Luca ,  RIEGER, Daniel K. ,  ROTHENBERG, Mark E. ,  SHENOY, Suresh G. ,  SMITHSON, Glennda ,  SPYTEK, Kimberly A. ,  STONE, David J. ,  TAUPIER, Raymond J., Jr. ,  TCHERNEV, Velizar T. ,  VERNET, Corine A. M. ,  VOSS, Edward Z. ,  ZERHUSEN, Bryan D. ,  ZHONG, Haihong ,  MILLER, Charles E.

IPC分类号： C07K14/00 ,  A61K38/17 ,  G01N33/53

CPC分类号： C07K14/705 ,  C07K14/47

摘要： Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the-polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

摘要翻译： 本文公开了编码G偶联蛋白质受体相关多肽的核酸序列。 还公开了由这些核酸序列编码的多肽，以及与多肽免疫特异性结合的抗体，以及上述多肽，多核苷酸或抗体的衍生物，变体，突变体或片段。 本发明进一步公开了用于诊断，治疗和预防涉及任何一种这些新型人核酸和蛋白质的疾病的治疗，诊断和研究方法。