公开(公告)号：EP1532238A2

公开(公告)日：2005-05-25

申请号：EP02778744.9

申请日：2002-11-05

申请人： Curagen Corporation

发明人： ALSOBROOK, John, P., II ,  ANDERSON, David, W. ,  BOLDOG, Ferenc, L. ,  BURGESS, Catherine, E. ,  CHANT, John, S. ,  CHAPOVAL, Andrei ,  CHAUDHURI, Amitabha ,  EDINGER, Shlomit, R. ,  EISEN, Andrew ,  GANGOLLI, Esha, A. ,  GERLACH, Valerie, L. ,  GUO, Xiaojia ,  JI, Weizhen ,  KHRAMTSOV, Nikolai, V. ,  LEITE, Mario, W. ,  LI, Li ,  MEZES, Peter, S. ,  MILLET, Isabelle ,  OOI, Chean, Eng ,  ORT, Tatiana ,  PADIGARU, Muralidhara ,  PATTURAJAN, Meera ,  PENA, Carol, E.A. ,  RASTELLI, Luca ,  RIEGER, Daniel, K. ,  QUINN SENGER, Kerry, E. ,  SMITHSON, Glennda ,  SPADERNA, Steven, K. ,  SPYTEK, Kiberly, A. ,  STONE, David, J. ,  TWOMLOW, Nancy ,  VERNET, Corine, A.M. ,  VOSS, Edward, Z. ,  ZERHUSEN, Bryan, D. ,  ZHIONG, Mei

IPC分类号： C12N9/00 ,  C12N1/20 ,  C12N5/00 ,  C12N15/00 ,  C12P21/04 ,  C12Q1/68 ,  C12Q1/00 ,  C07H21/04

CPC分类号： C12N9/00 ,  A61K38/00 ,  A61K48/00 ,  C07K14/47

摘要： Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.