公开(公告)号：EP2775836B8

公开(公告)日：2018-10-24

申请号：EP11875217.9

申请日：2011-11-04

Applicant: CymaBay Therapeutics, Inc. ,  DiaTex, Inc.

Inventor： LAVAN, Brian Edward ,  SAHA, Gopal Chandra ,  ROBERTS, Brian K. ,  MCWHERTER, Charles A.

IPC: A61P19/06

CPC classification number: A61K31/216 ,  A61K31/047 ,  A61K31/09 ,  A61K31/192 ,  A61K31/195 ,  A61K31/343 ,  A61K31/352 ,  A61K31/40 ,  A61K31/4178 ,  A61K31/4192 ,  A61K31/4196 ,  A61K31/426 ,  A61K31/4422 ,  A61K31/519 ,  A61K31/573 ,  A61K31/6615 ,  A61K45/06 ,  A61P19/06 ,  A61K2300/00

Abstract: Methods of treating gout flares comprising administering a composition comprising a first urate-lowering agent are disclosed. In some aspects, the first urate-lowering agent is (-)- halofenate, (-)-halofenic acid, or a pharmaceutically acceptable salt thereof. Other aspects provide for methods of reducing the number, duration, frequency or intensity of gout flares experienced by a subject.

公开(公告)号：EP2775836B1

公开(公告)日：2018-09-12

申请号：EP11875217.9

申请日：2011-11-04

Applicant: CymaBay Therapeutics, Inc. ,  DiaTex, Inc.

Inventor： LAVAN, Brian Edward ,  SAHA, Gopal Chandra ,  ROBERTS, Brian K. ,  MCWHERTER, Charles A.

IPC: A61P19/06

CPC classification number: A61K31/216 ,  A61K31/047 ,  A61K31/09 ,  A61K31/192 ,  A61K31/195 ,  A61K31/343 ,  A61K31/352 ,  A61K31/40 ,  A61K31/4178 ,  A61K31/4192 ,  A61K31/4196 ,  A61K31/426 ,  A61K31/4422 ,  A61K31/519 ,  A61K31/573 ,  A61K31/6615 ,  A61K45/06 ,  A61P19/06 ,  A61K2300/00

Abstract: Methods of treating gout flares comprising administering a composition comprising a first urate-lowering agent are disclosed. In some aspects, the first urate-lowering agent is (-)- halofenate, (-)-halofenic acid, or a pharmaceutically acceptable salt thereof. Other aspects provide for methods of reducing the number, duration, frequency or intensity of gout flares experienced by a subject.