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1.发明公开Compounds, compositions and methods of treatment for heart failure 审中-公开Verbindungen，Zusammensetzungen und Verfahren zur Behandlung von Herzinsuffizienz
公开(公告)号：EP2397462A2
公开(公告)日：2011-12-21
申请号：EP11181477.8
申请日：2004-01-14
申请人： Cytokinetics, Inc.
发明人： Morgan, Bradley, Paul , Elias, Kathleen A. , Kraynack, Erica Anne , Lu, Pu-Ping , Malik, Fady , Muci, Alex , Qian, Xiangping , Smith, Whitney Walter , Tachimoto, Todd , Tomasi, Adam Lewis , Morgans, David J. Jr.
IPC分类号： C07C273/02 , C07C275/34 , C07D213/02 , C07D207/12 , C07D401/12 , C07D413/12 , A61K31/17 , A61K31/44 , A61P9/04
CPC分类号： A61K31/44 , A61K31/17 , C07C275/30 , C07C275/34 , C07C275/36 , C07C275/40 , C07D207/12 , C07D211/42 , C07D213/65 , C07D213/70 , C07D213/75 , C07D217/04 , C07D401/12 , C07D405/12 , C07D413/12 , C07D417/12 , C07D498/04 , C07D513/04
摘要： Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
摘要翻译： 某些取代的脲衍生物选择性调节心肌肉瘤，例如通过增强心肌肌球蛋白，并且可用于治疗包括充血性心力衰竭的收缩性心力衰竭。
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2.发明公开
公开(公告)号：EP2397462A3
公开(公告)日：2012-04-04
申请号：EP11181477.8
申请日：2004-01-14
申请人： Cytokinetics, Inc.
发明人： Morgan, Bradley, Paul , Elias, Kathleen A. , Kraynack, Erica Anne , Lu, Pu-Ping , Malik, Fady , Muci, Alex , Qian, Xiangping , Smith, Whitney Walter , Tachimoto, Todd , Tomasi, Adam Lewis , Morgans, David J. Jr.
IPC分类号： C07C273/02 , C07C275/34 , C07D213/02 , C07D207/12 , C07D401/12 , C07D413/12 , A61K31/17 , A61K31/44 , A61P9/04
CPC分类号： A61K31/44 , A61K31/17 , C07C275/30 , C07C275/34 , C07C275/36 , C07C275/40 , C07D207/12 , C07D211/42 , C07D213/65 , C07D213/70 , C07D213/75 , C07D217/04 , C07D401/12 , C07D405/12 , C07D413/12 , C07D417/12 , C07D498/04 , C07D513/04
摘要： Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
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