公开(公告)号：EP1293497A4

公开(公告)日：2005-04-27

申请号：EP01943812

申请日：2001-06-22

申请人： DAIICHI FINE CHEM CO LTD

发明人： TAKAHASHI NORIKAZU ,  NOZAKI TOMOKO ,  EIMORI SOTOHIKO ,  SHIBA MOTOO

IPC分类号： A61P3/02 ,  A61P17/00 ,  A61P29/00 ,  C07C231/24 ,  C07C235/12 ,  A61K31/197

CPC分类号： C07C235/12 ,  C07C231/24

摘要： A process for the production of crystalline calcium pantothenate which comprises subjecting a homogeneous mixture containing both crystalline calcium pantothenate and amorphous calcium pantothenate to moisture absorption. This process comprises, e.g., the following steps of: (1) mixing crystalline calcium pantothenate with amorphous calcium pantothenate to form a homogeneous mixture and (2) making the obtained homogeneous mixture absorb moisture, and permits efficient production of extremely lowly hygroscopic crystalline calcium pantothenate.

公开(公告)号：EP1142866A4

公开(公告)日：2003-05-28

申请号：EP99961316

申请日：1999-12-22

申请人： DAIICHI FINE CHEM CO LTD

发明人： TAKAHASHI NORIKAZU ,  NOZAKI TOMOKO ,  EIMORI SOTOHIKO ,  SHIBA MOTOO

IPC分类号： C07C231/24 ,  C07C235/12

CPC分类号： C07C231/24 ,  C07C235/12

摘要： A method for producing nondeliquescent, crystalline calcium pantothenate comprising the steps of: (1) stirring a supersaturated aqueous solution containing calcium pantothenate in a proportion of 60 % (W/W) or more with, for example, a wet crusher to prepare a suspension of crystals; and (2) drying the suspension. The method can be used for efficiently producing nondeliquescent, crystalline calcium pantothenate which is substantially free of an organic solvent.