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公开(公告)号:EP1371731A4
公开(公告)日:2005-12-14
申请号:EP02701683
申请日:2002-03-01
发明人: SAKAMOTO K , KITA S , TSUZAKI K , MORIKAWA T , SHIMIZU S , KATAOKA M
IPC分类号: C12N1/15 , C12N1/19 , C12N1/21 , C12N9/04 , C12N15/53 , C12P13/00 , C12N5/10 , C12N9/02 , C12P7/02
CPC分类号: C12N9/0006 , C12P13/001 , C12P13/008
摘要: A protein which is an aminoketone asymmetric reductase acting on 1-2-methylaminopropiophenone to form d-pseudoephedrine and having the following physicochemical properties; and a nucleic acid encoding this protein: substrate: 1-2-methylaminopropiophenone; optimum pH value: 8.1; optimum temperature: 55 °C; coenzyme: NADP; and molecular weight: homotetramer of about 28500 Da.