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公开(公告)号:EP1001035B9
公开(公告)日:2006-11-08
申请号:EP97919709.2
申请日:1997-04-25
发明人: KIMURA, Ken-ichi , IKEDA, Yoshikazu , KAGAMI, Shinobu, Matsubara mansion 2A , TAKAHASHI, Hidetoshi , TAKAHASHI, Kousaku , YOSHIHAMA, Makoto , UBUKATA, Makoto , ISONO, Kiyoshi
CPC分类号: C07H19/06 , C12P19/385
摘要: Antibiotics RK-1061 having a novel chemical structure and a process for preparing the same. They have a structural formula represented by general formula (I) wherein A represents R1 or R1CH(OR2)CH2, R2 represents a 3-methylglutaric acid residue and R3 represents a sulfate group or a hydrogen atom. The process comprises culturing a ray fungus belonging to the genus Streptomyces and isolating RK-1061 from the culture. Streptomyces sp.SN-1061M (FERM BP-5800) is capable of stably producing RK-1061 at a high productivity.
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公开(公告)号:EP1001035B1
公开(公告)日:2006-01-11
申请号:EP97919709.2
申请日:1997-04-25
发明人: KIMURA, Ken-ichi , IKEDA, Yoshikazu , KAGAMI, Shinobu, Matsubara mansion 2A , TAKAHASHI, Hidetoshi , TAKAHASHI, Kousaku , YOSHIHAMA, Makoto , UBUKATA, Makoto , ISONO, Kiyoshi
CPC分类号: C07H19/06 , C12P19/385
摘要: Antibiotics RK-1061 having a novel chemical structure and a process for preparing the same. They have a structural formula represented by general formula (I) wherein A represents R1 or R1CH(OR2)CH2, R2 represents a 3-methylglutaric acid residue and R3 represents a sulfate group or a hydrogen atom. The process comprises culturing a ray fungus belonging to the genus Streptomyces and isolating RK-1061 from the culture. Streptomyces sp.SN-1061M (FERM BP-5800) is capable of stably producing RK-1061 at a high productivity.
摘要翻译: 具有新型化学结构的抗生素RK-1061及其制备方法。 它们具有由通式(I)表示的结构式,其中A表示R 1或R 1 CH(OR 2)CH 2,R 2表示3-甲基戊二酸残基,并且R 3表示硫酸根基团或氢原子。 该方法包括培养属于链霉菌属的射线真菌并从培养物中分离RK-1061。 Streptomyces sp.SN-1061M(FERM BP-5800)能够以高生产力稳定生产RK-1061。
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