公开(公告)号：EP1188760A4

公开(公告)日：2002-08-07

申请号：EP00929862

申请日：2000-05-25

申请人： DAIICHI SEIYAKU CO ,  NAGANO TESTUO

发明人： NAGANO TETSUO ,  KIKUCHI KAZUYA ,  INOUE TAKANARI ,  IINO MASAMITSU ,  HIROSE KENZO

IPC分类号： A61P43/00 ,  C07F9/117 ,  C07F9/655 ,  C07F9/6561 ,  C07F9/144 ,  A61K31/661 ,  A61K41/00 ,  C07D493/10

CPC分类号： C07F9/6561 ,  C07F9/117 ,  C07F9/65522

摘要： Compounds of general formula (I) or salts thereof, useful as ligands to inositol 1,4,5-trisphosphate (IP3) receptor, wherein R is a group represented by general formula (A), (B) or (C) (wherein R and R are each independently C1-6 alkyl; R is amino, mono(C1-6 alkyl)amino, di(C1-6 alkyl)amino, or C1-6 alkoxy; and X is an anion); and n is an integer of 2 to 5.