公开(公告)号：EP1663177A1

公开(公告)日：2006-06-07

申请号：EP04780975.1

申请日：2004-08-13

申请人： DOW CORNING CORPORATION ,  GENENCOR INTERNATIONAL, INC.

发明人： BOTT, Richard, R. ,  GEBERT, Mark, S. ,  KLYKKEN, Paal, Christian ,  MAZEAUD, Isabelle ,  THOMAS, Xavier, Jean-Paul

IPC分类号： A61K9/70 ,  A61K38/16 ,  A61K38/18 ,  A61K38/19 ,  A61K38/46 ,  A61K38/48 ,  A61K47/32 ,  A61K47/34 ,  A61P7/02 ,  A61P7/12

CPC分类号： A61K9/7069 ,  A61K9/0014 ,  A61K9/7007 ,  A61K38/465 ,  A61K38/482 ,  A61K47/02 ,  A61K47/24 ,  A61K47/34 ,  A61L26/0019 ,  A61L26/0066 ,  A61L2300/254 ,  A61L2300/602 ,  A61L2300/622 ,  C08L83/04

摘要： Topical preparations for release of an active agent to remove necrotic tissue and to methods of making and using the topical preparations are provided. The preparations may have an internal phase dispersed within an external phase. The internal phase may be a hydrophilic carrier and an active agent. The external phase may be a silicone matrix.

公开(公告)号：EP1487462A2

公开(公告)日：2004-12-22

申请号：EP03756147.9

申请日：2003-03-11

申请人： Dow Corning Corporation ,  GENENCOR INTERNATIONAL, INC.

发明人： BOTT, Richard, R. ,  GEBERT, Mark, S. ,  KLYKKEN, Paal, Christian ,  MAZEAUD, Isabelle ,  THOMAS, Xavier, Jean-Paul

IPC分类号： A61K31/74

CPC分类号： A61K47/24 ,  A61K9/0014 ,  A61K9/7007 ,  A61K9/7069 ,  A61K38/465 ,  A61K38/482 ,  A61L26/0019 ,  A61L26/0066 ,  A61L2300/254 ,  A61L2300/602 ,  A61L2300/622 ,  C08L83/04

摘要： The present invention is related to topical preparations for release of an active agent and to methods of making and using the topical preparations. The preparations may have an internal phase dispersed within an external phase. The internal phase may be a hydrophilic carrier and an active agent. The external phase may be a silicone matrix. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that is will not be used to interpret or limit the scope or meaning of the claims.

公开(公告)号：EP1663177B1

公开(公告)日：2010-03-17

申请号：EP04780975.1

申请日：2004-08-13

申请人： Dow Corning Corporation ,  GENENCOR INTERNATIONAL, INC.

发明人： BOTT, Richard, R. ,  GEBERT, Mark, S. ,  KLYKKEN, Paal, Christian ,  MAZEAUD, Isabelle ,  THOMAS, Xavier, Jean-Paul

IPC分类号： A61K9/70 ,  A61K38/16 ,  A61K38/18 ,  A61K38/19 ,  A61K38/46 ,  A61K38/48 ,  A61K47/32 ,  A61K47/34 ,  A61P7/02 ,  A61P7/12

CPC分类号： A61K9/7069 ,  A61K9/0014 ,  A61K9/7007 ,  A61K38/465 ,  A61K38/482 ,  A61K47/02 ,  A61K47/24 ,  A61K47/34 ,  A61L26/0019 ,  A61L26/0066 ,  A61L2300/254 ,  A61L2300/602 ,  A61L2300/622 ,  C08L83/04

公开(公告)号：EP1680097B1

公开(公告)日：2009-03-11

申请号：EP04796563.7

申请日：2004-10-27

申请人： Dow Corning Corporation ,  GENENCOR INTERNATIONAL, INC.

发明人： BOTT, Richard, R. ,  BRANDSTADT, Kurt, Friedrich ,  KOLLAR, Csilla ,  LANE, Thomas, Howard ,  LILES, Donald, Taylor ,  SALDJENO, Mae ,  THOMAS, Xavier, Jean-Paul

IPC分类号： A61K9/70

CPC分类号： A61K9/107 ,  A61K8/06 ,  A61K8/062 ,  A61K8/89 ,  A61K9/0014 ,  A61K47/24 ,  A61K47/30 ,  A61Q19/00

公开(公告)号：EP1680097A1

公开(公告)日：2006-07-19

申请号：EP04796563.7

申请日：2004-10-27

申请人： DOW CORNING CORPORATION ,  GENENCOR INTERNATIONAL, INC.

发明人： BOTT, Richard, R. ,  BRANDSTADT, Kurt, Friedrich ,  KOLLAR, Csilla ,  LANE, Thomas, Howard ,  LILES, Donald, Taylor ,  SALDJENO, Mae ,  THOMAS, Xavier, Jean-Paul

IPC分类号： A61K9/70

CPC分类号： A61K9/107 ,  A61K8/06 ,  A61K8/062 ,  A61K8/89 ,  A61K9/0014 ,  A61K47/24 ,  A61K47/30 ,  A61Q19/00

摘要： A multi-layer dressing and controlled-release composition for topical application to a substrate include an emulsion and an active agent incorporated into the emulsion. The active agent includes a protein. A method of delivering the active agent to the substrate provides the emulsion and incorporates the active agent into the emulsion for delivery of the active agent to the substrate.

公开(公告)号：EP1737504A1

公开(公告)日：2007-01-03

申请号：EP05726039.0

申请日：2005-03-18

申请人： DOW CORNING CORPORATION

发明人： GANTNER, David, Clayton ,  THOMAS, Xavier, Jean-Paul

IPC分类号： A61L24/04 ,  A61L15/58 ,  C09J183/04 ,  C08L83/04

CPC分类号： A61L24/046 ,  A61L15/58 ,  C08L83/04

摘要： A method for adhering a medical substrate to a human or animal using a silicone gel containing a hydroxy substituted siloxane resin.

摘要翻译： 使用含有羟基取代的硅氧烷树脂的硅凝胶将医学基材粘合到人或动物上的方法。

公开(公告)号：EP1737504B1

公开(公告)日：2010-06-09

申请号：EP05726039.0

申请日：2005-03-18

申请人： Dow Corning Corporation

发明人： GANTNER, David, Clayton ,  THOMAS, Xavier, Jean-Paul

IPC分类号： A61L24/04 ,  A61L15/58 ,  C09J183/04 ,  C08L83/04

CPC分类号： A61L24/046 ,  A61L15/58 ,  C08L83/04

摘要： A method for adhering a medical substrate to a human or animal using a silicone gel containing a hydroxy substituted siloxane resin.

公开(公告)号：EP1976956A2

公开(公告)日：2008-10-08

申请号：EP07716232.9

申请日：2007-01-03

申请人： Dow Corning Corporation

发明人： SCHALAU, Gerald, Kenneth, II ,  THOMAS, Xavier, Jean-Paul ,  RAUL, Victor, Albert ,  GANTNER, David, Clayton

IPC分类号： C09J183/04 ,  A61K9/70

CPC分类号： A61K9/7069 ,  A61K9/7007 ,  A61M5/14248 ,  A61M2205/0205 ,  A61M2205/0238 ,  C08G2170/40 ,  C08L83/00 ,  C09J183/04

摘要： A silicone adhesive composition used for adhering a device or a substance to a wet surface contains (i) a silicone resin that is cohydrolysis product of a trialkyl hydrolyzable silane and an alkyl silicate in which the cohydrolysis product contains a plurality of silicon-bonded hydroxy groups; (ii) a linear organopolysiloxane fluid containing terminal silicon-bonded hydroxy groups having a viscosity above 200,000 mm2/s at 25° C.; (iii) a trialkylsiloxy terminated polyorganosiloxane fluid having a viscosity of 100,000-600,000 mm2/s at 25° C.; (iv) a water soluble muco-adhesive polymer selected from the group consisting of a poly(ethylene oxide) polymer having a molecular weight of 100,000 to 8,000,000, an acrylic acid polymer having a molecular weight of 500,000 to 4,500,000,000, and a hydroxyethylcellulose polymer having a molecular weight of 90,000 to 1,300,000,000; and optionally, (v) a solvent selected from the group consisting of aliphatic hydrocarbons, aromatic hydrocarbons, esters, volatile linear and cyclic silicone compounds. Other components such as a silicone polyether, a silicone wax, a drug, an excipient, and/or an active ingredient can also be included.

公开(公告)号：EP1684814B1

公开(公告)日：2014-10-22

申请号：EP04785363.5

申请日：2004-09-30

申请人： Dow Corning Corporation

发明人： GANTNER, David, Clayton ,  LOUBERT, Gary Lee ,  SCHALAU, Gerald, Kenneth, II ,  THOMAS, Xavier, Jean-Paul

IPC分类号： A61L15/58

CPC分类号： A61L15/58 ,  A61L24/046 ,  A61L31/06 ,  C08L83/00 ,  C09J5/02 ,  C08L83/04

公开(公告)号：EP1793811A1

公开(公告)日：2007-06-13

申请号：EP05777652.8

申请日：2005-07-27

申请人： Dow Corning Corporation

发明人： MURPHY, Kevin, Patrick ,  SCHALAU, Gerald, Kenneth, II ,  THOMAS, Xavier, Jean-Paul

IPC分类号： A61K9/70

CPC分类号： A61Q15/00 ,  A61F13/02 ,  A61K8/0212 ,  A61K8/26 ,  A61K8/28 ,  A61K8/44 ,  A61K8/891 ,  A61K8/892 ,  A61K8/895 ,  A61L15/18 ,  A61L15/58 ,  C08L83/04

摘要： This invention relates to a method of enhancing the adhesion of a silicone containing adhesive formulation. The method comprises mixing 1 to 99.9 wt. % of a silicone-containing adhesive formulation and 0.1 to 50 wt. % antiperspirant compound to form a composition. The composition is then applied onto a surface and allowed to cure. The invention also relates to a composition comprising 1 to 99.9 wt. % of a silicone-containing adhesive formulation and 0.1 to 50 wt. % antiperspirant salt. The resultant adhesive films are especially useful in healthcare and cosmetic applications where they inhibit perspiration and, thus, retain the adhesive strength of the adhesive.