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1.发明公开
公开(公告)号：EP4056708A1
公开(公告)日：2022-09-14
申请号：EP21196529.8
申请日：2010-03-22
申请人： DSM IP Assets B.V.
发明人： APT, Kirk E. , BEHRENS, Paul Warren , HANSEN, Jon Milton , PFEIFER III, Joseph W. , STAHL, Tracey Lynn , ZIRKLE, Ross
IPC分类号： C12P19/34 , C12N1/14 , C12R1/89 , A23L33/115 , A23K50/00
摘要： Isolated microorganisms as well as strains and mutants thereof, biomasses, microbial oils, compositions, and cultures; methods of producing the microbial oils, biomasses, and mutants; and methods of using the isolated microorganisms, biomasses, and microbial oils.
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公开(公告)号：EP3926050A1
公开(公告)日：2021-12-22
申请号：EP21176828.8
申请日：2009-03-19
申请人： DSM IP Assets B.V.
发明人： APT, Kirk E. , PFEIFER III, Joseph W. , HANSEN, Jon Milton , BEHRENS, Paul Warren , ZIRKLE, Ross , STAHL, Tracey Lynn
摘要： The present invention is directed to isolated thraustochytrid microorganisms as well as strains and mutants thereof. The invention is further directed to biomasses, microbial oils, compositions, cultures, methods of producing microbial oils, and methods of using the isolated thraustochytrids, biomasses, and microbial oils.
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3.发明授权RECOMBINANT THRAUSTOCHYTRIDS THAT GROW ON XYLOSE, AND COMPOSITIONS, METHODS OF MAKING, AND USES THEREOF 有权重组THRAUSTOCHYTRIDS生长于木糖上，及其组合物，制备方法及其用途
公开(公告)号：EP2519642B1
公开(公告)日：2017-10-25
申请号：EP10844275.7
申请日：2010-12-28
申请人： DSM IP Assets B.V.
CPC分类号： C12N1/10 , A23K50/00 , A23K50/80 , A23L2/52 , A23L33/10 , A23V2002/00 , C12N1/22 , C12N15/52 , C12N15/79 , C12P7/649 , Y02E50/13
摘要： The present invention is directed to recombinant thraustochytrids that grow on xylose and cell cultures comprising the recombinant thraustochytrids as well as methods of producing cell cultures, biomasses, microbial oils, compositions, and biofuels using the recombinant thraustochytrids.
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4.发明公开THRAUSTOCHYTRIDS, FATTY ACID COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF 审中-公开THRAUSTOCHYTRIDS，脂肪酸组合物及其制备和使用方法
公开(公告)号：EP3196309A2
公开(公告)日：2017-07-26
申请号：EP16180878.7
申请日：2009-03-19
申请人： DSM IP Assets B.V.
发明人： APT, Kirk E. , PFEIFER, III, Joseph W. , HANSEN, Jon Milton , BEHRENS, Paul Warren , ZIRKLE, Ross , STAHL, Tracey Lynn
CPC分类号： C12R1/89 , C12N1/12 , C12P7/6427 , C12P7/6472
摘要： The present invention is directed to isolated thraustochytrid microorganisms as well as strains and mutants thereof. The invention is further directed to biomasses, microbial oils, compositions, cultures, methods of producing microbial oils, and methods of using the isolated thraustochytrids, biomasses, and microbial oils.
摘要翻译： 本发明涉及分离的破囊壶菌微生物以及其菌株和突变体。 本发明还涉及生物质，微生物油，组合物，培养物，生产微生物油的方法以及使用分离的破囊壶菌目生物质和微生物油的方法。
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公开(公告)号：EP2952183A1
公开(公告)日：2015-12-09
申请号：EP15171728.7
申请日：2012-07-20
申请人： DSM IP Assets B.V.
发明人： APT, Kirk E. , BEHRENS, Paul Warren , HANSEN, Jon Milton , PFEIFER, III, Joseph W. , STAHL, Tracey Lynn , ZIRKLE, Ross
IPC分类号： A61K31/202 , C12P7/64
CPC分类号： A61K31/202 , A23K20/158 , A23K50/80 , A23L2/52 , A23L33/12 , A23L33/40 , A23V2002/00 , A61K8/361 , A61K2800/10 , A61Q19/00 , C12P7/6427 , A61K2300/00
摘要： The disclosure is directed to microbial oils containing omega-3 polyunsaturated fatty acids comprising docosahexaenoic acid, eicosapentaenoic acid, and optionally docosapentaenoic acid and dosage forms containing such oils.
摘要翻译： 本公开涉及含有ω-3多不饱和脂肪酸的微生物油，其包含二十二碳六烯酸，二十碳五烯酸和任选的二十二碳五烯酸以及含有这种油的剂型。
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6.发明公开EICOSAPENTAENOIC ACID-PRODUCING MICROORGANISMS, FATTY ACID COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF 审中-公开二十碳五烯酸的微生物用于生产和使用，脂肪酸组合物和方法
公开(公告)号：EP2734630A2
公开(公告)日：2014-05-28
申请号：EP12815192.5
申请日：2012-07-20
申请人： DSM IP Assets B.V.
发明人： PFEIFER, III, Joseph W. , HANSEN, Jon Milton , DONG, Xiao Daniel , BEHRENS, Paul Warren , APT, Kirk E. , GARCIA, Jose R.
IPC分类号： C12P7/64
摘要： The present invention is directed to isolated microorganisms as well as strains and mutants thereof, biomasses, microbial oils, compositions, and cultures; methods of producing the microbial oils, biomasses, and mutants; and methods of using the isolated microorganisms, biomasses, and microbial oils.
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公开(公告)号：EP2734630B1
公开(公告)日：2019-12-25
申请号：EP12815192.5
申请日：2012-07-20
申请人： DSM IP Assets B.V.
发明人： PFEIFER, III, Joseph W. , HANSEN, Jon Milton , DONG, Xiao Daniel , BEHRENS, Paul Warren , APT, Kirk E. , GARCIA, Jose R.
IPC分类号： C12P7/64
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公开(公告)号：EP3196309B1
公开(公告)日：2019-09-04
申请号：EP16180878.7
申请日：2009-03-19
申请人： DSM IP Assets B.V.
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公开(公告)号：EP3192871B1
公开(公告)日：2019-01-23
申请号：EP17153399.5
申请日：2010-03-19
申请人： DSM IP Assets B.V.
发明人： APT, Kirk E. , RICHTER, Leslie , SIMPSON, David , ZIRKLE, Ross
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10.发明公开POLYUNSATURATED FATTY ACID SYNTHASE NUCLEIC ACID MOLECULES AND POLYPEPTIDES, COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF 审中-公开多不饱和脂肪酸合成酶核酸分子和多肽，组合物及其制备和使用方法
公开(公告)号：EP3192871A1
公开(公告)日：2017-07-19
申请号：EP17153399.5
申请日：2010-03-19
申请人： DSM IP Assets B.V.
发明人： APT, Kirk E. , RICHTER, Leslie , SIMPSON, David , ZIRKLE, Ross
CPC分类号： C12N15/52 , A61K38/00 , C12N9/0006 , C12N9/001 , C12N9/1029 , C12N9/88 , C12N15/8247 , C12P7/6427 , C12P7/6472 , C12Y101/01 , C12Y103/01 , C12Y203/01039 , C12Y203/01041 , C12Y402/01 , C12Y402/01059 , Y02P20/52
摘要： The present invention is directed to isolated nucleic acid molecules and polypeptides of thraustochytrid polyunsaturated fatty acid (PUFA) synthases involved in the production of the PUFAs, including PUFAs enriched in docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), or a combination thereof. The present invention is directed to vectors and host cells comprising the nucleic acid molecules, polypeptides encoded by the nucleic acid molecules, compositions comprising the nucleic acid molecules or polypeptides, and methods of making and uses thereof.
摘要翻译： 本发明涉及涉及生产PUFA的破囊壶菌多不饱和脂肪酸（PUFA）合酶的分离的核酸分子和多肽，包括富含二十二碳六烯酸（DHA），二十碳五烯酸（EPA）或其组合的PUFA。 本发明涉及包含核酸分子，由核酸分子编码的多肽，包含核酸分子或多肽的组合物的载体和宿主细胞，以及其制备和使用方法。
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