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公开(公告)号：EP2150559B1
公开(公告)日：2016-02-10
申请号：EP08801456.8
申请日：2008-06-09
申请人： DSM IP Assets B.V.
CPC分类号： C12N15/75 , C12P1/04 , C12P13/02 , C12P17/12 , C12P17/167 , C12P17/182 , C12P17/186 , C12P21/02 , C12P25/00
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公开(公告)号：EP1957651A1
公开(公告)日：2008-08-20
申请号：EP06818946.3
申请日：2006-12-01
申请人： DSM IP Assets B.V.
CPC分类号： C12N15/67
摘要： A method to increase the production of a desired chemical compound in a microorganism by introduction of a DNA sequence at the 5' end of the encoding DNA gene sequence capable of forming a stem loop and capable of increasing the stability of mRNA transcripts from one or more genes, thus stabilized mRNAs, corresponding DNA sequences and microorganisms.
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公开(公告)号：EP1957651B1
公开(公告)日：2014-03-05
申请号：EP06818946.3
申请日：2006-12-01
申请人： DSM IP Assets B.V.
CPC分类号： C12N15/67
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公开(公告)号：EP2150559A2
公开(公告)日：2010-02-10
申请号：EP08801456.8
申请日：2008-06-09
申请人： DSM IP Assets B.V.
CPC分类号： C12N15/75 , C12P1/04 , C12P13/02 , C12P17/12 , C12P17/167 , C12P17/182 , C12P17/186 , C12P21/02 , C12P25/00
摘要： The present invention relates to newly identified mRNA stabilizing elements useful for the production of a target fermentation product, such as e.g. vitamins or enzymes, in particular riboflavin (vitamin B2), biotin, pantothenic acid (vitamin B5), folic acid, thiamin, pyridoxine (vitamin B6), vitamin B12, xylanase, amylase, protease, glucanase, amylomaltase or maltogenic amylase.
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