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    Novel biosensor system based on recognition induced birefringence (RIB)
    1.
    发明公开
    Novel biosensor system based on recognition induced birefringence (RIB) 有权
    Neuartiges Biosensorsystem basierend auf der Erkennung von induzierter Doppelbrechung（RIB）

    公开(公告)号：EP2204650A1

    公开(公告)日：2010-07-07

    申请号：EP08022585.7

    申请日：2008-12-31

    申请人： DWI an der RWTH Aachen e.V.

    发明人： Groll, Jürgen, Dr. ,  Möller, Martin ,  Eberhardt, Matthias, Dr.

    IPC分类号： G01N33/543 ,  B01J19/00

    CPC分类号： G01N33/54393 ,  B01J2219/00509 ,  B01J2219/00605 ,  B01J2219/00612 ,  B01J2219/00621 ,  B01J2219/00623 ,  B01J2219/00635 ,  B01J2219/00637 ,  B01J2219/00702 ,  G01N33/54373

    摘要： The present invention relates to a label-free biosensor system, a method for manufacturing said label-free biosensor system, its use for detecting biochemical reactions and/or bindings, enzymatic reactions, nucleic acid hybridizations, protein-protein interactions and protein-ligand interactions, as well as an assay method for detecting and/or quantifying an analyte of interest in a biological sample which comprises detecting the Recognition Induced Birefringence (RIB) generated in the presence as opposed to the absence of said analyte by bringing said sample into contact with said label-free biosensor system.

    摘要翻译： 本发明涉及无标记生物传感器系统，制造所述无标记生物传感器系统的方法，其用于检测生化反应和/或结合的用途，酶反应，核酸杂交，蛋白质 - 蛋白质相互作用和蛋白质 - 配体相互作用 以及用于检测和/或定量生物样品中感兴趣分析物的测定方法，其包括检测在存在时产生的识别诱导双折射（RIB），而不是通过使所述样品与所述分析物接触而不存在所述分析物 所述无标签的生物传感器系统。