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1.发明授权SERINE PROTEASES, NUCLEIC ACIDS ENCODING SERINE ENZYMES AND VECTORS AND HOST CELLS INCORPORATING SAME 有权丝氨酸蛋白酶FOR SERINENZYME CODING NUCLEIC和这条腿AMUSING载体和宿主细胞
公开(公告)号：EP1694847B1
公开(公告)日：2012-06-13
申请号：EP04811731.1
申请日：2004-11-19
发明人： JONES, Brian, Edward , KOLKMAN, Marc , LEEFLANG, Chris , OH, Hiroshi , POULOSE, Ayrookaran, J. , SADLOWSKI, Eugene, S. , SHAW, Andrew , VAN DER KLEIJ, Wilhelmus, A., H. , VAN MARREWIJK, Leo
IPC分类号： C12N15/53
CPC分类号： C12N9/52 , C07K2299/00 , C11D3/386
摘要： The present invention provides novel serine proteases, novel genetic material encoding these enzymes, and proteolytic proteins obtained from Micrococcineae spp., including but not limited to Cellulomonas spp. and variant proteins developed therefrom. In particular, the present invention provides protease compositions obtained from a Cellulomonas spp, DNA encoding the protease, vectors comprising the DNA encoding the protease, host cells transformed with the vector DNA, and an enzyme produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising protease(s) obtained from a Micrococcineae spp., including but not limited to Cellulomonas spp. In alternative embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These mutant proteases also find use in numerous applications.
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2.发明公开SERINE PROTEASES, NUCLEIC ACIDS ENCODING SERINE ENZYMES AND VECTORS AND HOST CELLS INCORPORATING SAME 有权丝氨酸蛋白酶FOR SERINENZYME CODING NUCLEIC和这条腿AMUSING载体和宿主细胞
公开(公告)号：EP1694847A2
公开(公告)日：2006-08-30
申请号：EP04811731.1
申请日：2004-11-19
发明人： JONES, Brian, Edward , KOLKMAN, Marc , LEEFLANG, Chris , OH, Hiroshi , POULOSE, Ayrookaran, J. , SADLOWSKI, Eugene, S. , SHAW, Andrew , VAN DER KLEIJ, Wilhelmus, A., H. , VAN MARREWIJK, Leo
IPC分类号： C12N15/53
CPC分类号： C12N9/52 , C07K2299/00 , C11D3/386
摘要： The present invention provides novel serine proteases, novel genetic material encoding these enzymes, and proteolytic proteins obtained from Micrococcineae spp., including but not limited to Cellulomonas spp. and variant proteins developed therefrom. In particular, the present invention provides protease compositions obtained from a Cellulomonas spp, DNA encoding the protease, vectors comprising the DNA encoding the protease, host cells transformed with the vector DNA, and an enzyme produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising protease(s) obtained from a Micrococcineae spp., including but not limited to Cellulomonas spp. In alternative embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These mutant proteases also find use in numerous applications.
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公开(公告)号：EP2084273A1
公开(公告)日：2009-08-05
申请号：EP07837430.3
申请日：2007-08-29
发明人： AEHLE, Wolfgang , ESTELL, David A. , HOMMES, Ronaldus W.J. , JONES, Brian E. , KOLKMAN, Marc , LEEFLANG, Chris , OH, Hiroshi , POULOSE, Ayrookaran J. , SHAW, Andrew , VAN DER KLEIJ, Wilhelmus A. H. , VAN MARREWIJK, Leo
CPC分类号： C12N9/52 , A23K20/189 , A23K50/75 , C11D3/386 , C12N9/96 , C12Y304/21 , D06M16/003
摘要： The present invention provides Micrococcineae spp serine proteases having multiple substitutions. In particular, the present invention provides serine proteases having multiple substitutions, DNA encoding these proteases, vectors comprising the DNA encoding the proteases, host cells transformed with the vector DNA, and enzymes produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising these serine protease variants. In particularly preferred embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These variant proteases also find use in numerous applications.
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