公开(公告)号：EP0934430A1

公开(公告)日：1999-08-11

申请号：EP97912018.0

申请日：1997-09-25

申请人： Deutsches Krebsforschungszentrum ,  Ruprecht-Karls-Universität Heidelberg

发明人： DEBATIN, Klaus-Michael ,  LOS, Marek ,  HUG, Hubert

IPC分类号： C12Q1

CPC分类号： C12Q1/37 ,  G01N2333/96466

摘要： The invention relates to a method for apoptosis diagnosis in cells wherein the cells are loaded with a substrate for ICE/Ced3 family proteases and the protease reaction of the substrate is monitored by imaging methods. The invention also concerns a kit in order to carry out this method.

公开(公告)号：EP0934430B1

公开(公告)日：2001-12-12

申请号：EP97912018.5

申请日：1997-09-25

申请人： Deutsches Krebsforschungszentrum

发明人： DEBATIN, Klaus-Michael ,  LOS, Marek ,  HUG, Hubert

IPC分类号： C12Q1/37

CPC分类号： C12Q1/37 ,  G01N2333/96466

摘要： The invention relates to a method for apoptosis diagnosis in cells wherein the cells are loaded with a substrate for ICE/Ced3 family proteases and the protease reaction of the substrate is monitored by imaging methods. The invention also concerns a kit in order to carry out this method.