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公开(公告)号:EP4384959A2
公开(公告)日:2024-06-19
申请号:EP22856839.0
申请日:2022-08-12
申请人: Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts , Universität Heidelberg , Sill, Martin , Pfister, Stefan , Jones, David , von Deimling, Andreas , Capper, David , Hovestadt, Volker , Sahm, Felix , Schrimpf, Daniel
发明人: SILL, Martin , PFISTER, Stefan , JONES, David , VON DEIMLING, Andreas , CAPPER, David , HOVESTADT, Volker , SAHM, Felix , SCHRIMPF, Daniel
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公开(公告)号:EP4381513A1
公开(公告)日:2024-06-12
申请号:EP22761187.8
申请日:2022-08-04
申请人: Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts , Universität Heidelberg , Oxford Nanopore Technologies PLC
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公开(公告)号:EP3268492B1
公开(公告)日:2020-09-23
申请号:EP16710700.2
申请日:2016-03-11
申请人: Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts , Ruprecht-Karls-Universität Heidelberg
发明人: PFISTER, Stefan , VON DEIMLING, Andreas , JONES, David , CAPPER, David , HOVESTADT, Volker , SILL, Martin , BEWERUNGE-HUDLER, Melanie , SCHICK, Matthias
IPC分类号: C12Q1/68
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公开(公告)号:EP3268492A1
公开(公告)日:2018-01-17
申请号:EP16710700.2
申请日:2016-03-11
申请人: Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts , Ruprecht-Karls-Universität Heidelberg
发明人: PFISTER, Stefan , VON DEIMLING, Andreas , JONES, David , CAPPER, David , HOVESTADT, Volker , SILL, Martin , BEWERUNGE-HUDLER, Melanie , SCHICK, Matthias
IPC分类号: C12Q1/68
摘要: The present invention pertains to methods for classifying tumorous diseases based on their specific genomic DNA methylation profile. The invention provides a method that allows for a classification of a tumor sample obtained from a patient by analysing a multitude, preferably genome wide, collection of CpG positions by comparison to a classification rule derived from a set of methylation data acquired from pre-classified tumor species. The invention is in particular useful for classifying brain tumor samples since brain tumors are characterized by a large variety of distinct tumor species which have different prognostic values and require in the clinic a for each species developed treatment regime.
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