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1.发明授权SOLID DISPERSION COMPRISING A HIGHLY SUBSTITUTED HYDROXYALKYL METHYLCELLULOSE 有权FESTE散剂麻醉剂HOCHSUBSTITERERTER羟丙基甲基纤维素
公开(公告)号：EP2874607B1
公开(公告)日：2017-05-31
申请号：EP13740163.4
申请日：2013-07-12
发明人： GRASMAN, Nicholas S. , GUILLAUDEU, Steven J. , HALL, Mark, J. , SHRESTHA, Uma , ROSE, Maureen L. , PORTER, William W. , SPAULDING, Wesley J. , O'DONNELL, Kevin P. , ROGERS, True L.
IPC分类号： A61K9/14 , A61K9/16 , A61K31/343 , A61K31/4166 , A61K31/58 , A61K9/48 , A61K47/38
CPC分类号： A61K47/38 , A61K9/146 , A61K9/1652 , A61K9/4891 , A61K31/343 , A61K31/4166 , A61K31/58
摘要： A solid dispersion comprising at least one active ingredient in at least one hydroxyalkyl methylcellulose having a DS of from 1.0 to 2.7 and an MS of from 0.40 to 1.30, wherein DS is the degree of substitution of methoxyl groups and MS is the molar substitution of hydroxyalkoxyl groups, can be produced by extrusion or spray-drying.
摘要翻译： 在至少一种羟烷基甲基纤维素中的至少一种羟烷基甲基纤维素中含有至少一种活性成分的固体分散体，DS为1.0至2.7，MS为0.40至1.30，其中DS为甲氧基的取代度，MS为羟基烷氧基 组，可以通过挤出或喷雾干燥来生产。
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2.发明公开
公开(公告)号：EP2874607A1
公开(公告)日：2015-05-27
申请号：EP13740163.4
申请日：2013-07-12
发明人： GRASMAN, Nicholas S. , GUILLAUDEU, Steven J. , HALL, Mark, J. , SHRESTHA, Uma , ROSE, Maureen L. , PORTER, William W. , SPAULDING, Wesley J. , O'DONNELL, Kevin P. , ROGERS, True L.
IPC分类号： A61K9/14 , A61K9/16 , A61K31/343 , A61K31/415 , A61K31/58
CPC分类号： A61K47/38 , A61K9/146 , A61K9/1652 , A61K9/4891 , A61K31/343 , A61K31/4166 , A61K31/58
摘要： A solid dispersion comprising at least one active ingredient in at least one hydroxyalkyl methylcellulose having a DS of from 1.0 to 2.7 and an MS of from 0.40 to 1.30, wherein DS is the degree of substitution of methoxyl groups and MS is the molar substitution of hydroxyalkoxyl groups, can be produced by extrusion or spray-drying.
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