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公开(公告)号：EP2265605A1
公开(公告)日：2010-12-29
申请号：EP09722911.6
申请日：2009-03-18
发明人： KOLLA, Naveen, Kumar , MANNE, Nagaraju , GANGULA, Srinivas , NEELAM, Udaykumar , NAREDLA, Anitha , BADDAM, Sudhakar, Reddy , PATIL, Sumeet, Vishwasrao , TUMMALA, Arjunkumar , PEDDIREDDY, Subbareddy , SHINDE, Sachin, Gulabrao , SIGALA, Ashok , MUDUNURU, Satish Varma , TUMMIDI, Madhu, Kiran
IPC分类号： C07D403/12 , C07D235/28 , C07D235/24
CPC分类号： C07D401/12 , A61K9/1635 , A61K9/1652 , A61K47/6951 , B82Y5/00
摘要： Processes for the preparation of dexlansoprazole, an amorphous form of dexlansoprazole, a solid dispersion of amorphous dexlansoprazole and a pharmaceutically acceptable carrier, and processes for their preparation. Also provided are crystalline compounds 2-[(R)-[(4-chloro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole and 2-[(R)-[(4-nitro-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole, and methods for their preparation.
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公开(公告)号：EP2334685A2
公开(公告)日：2011-06-22
申请号：EP09812196.5
申请日：2009-09-03
发明人： KADABOINA, Rajasekhar , NARIYAM, Sekhar Munaswamy , RAMAKRISHNAN, Srividya , PEDDIREDDY, Subbareddy , BAIG, Mohammed, Azeezulla , DUGGIRALA, Nagakiran
IPC分类号： C07D487/04 , C07F1/04
CPC分类号： C07D487/04
摘要： Processes for the preparation of amorphous pemetrexed disodium, and removal of residual solvents from amorphous pemetrexed disodium.
摘要翻译： 制备无定形培美曲塞二钠的方法，以及从无定形培美曲塞二钠中除去残余溶剂的方法。
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公开(公告)号：EP2001481A2
公开(公告)日：2008-12-17
申请号：EP07759677.3
申请日：2007-03-29
发明人： MATHAD, Vijayavitthal, Thippannachar , VANKAWALA, Pravinchandra, Jayantilal , ELATI, Raviram, Chandrasekhar , MACHARLA, Prabhakar , GANGULA, Srinivas , KOLLA, Naveen, Kumar , KOMAREDDY, Ravi, Kumar , DEVARKONDA, Surya, Narayana , PEDDIREDDY, Subbareddy
IPC分类号： A61K31/5377 , C07D413/06
CPC分类号： C07D413/06
摘要： Intimate mixtures of aprepitant crystalline Form I and crystalline Form II, having specific weight ratios of the forms.
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