公开(公告)号：EP2247348A2

公开(公告)日：2010-11-10

申请号：EP08871506.5

申请日：2008-12-30

申请人： E-Z-EM, Inc.

发明人： HENRY, Timothy, G. ,  PRICE, Barbara, B.

IPC分类号： A62D3/30 ,  A62D3/33

CPC分类号： A62D3/36 ,  A61K8/40 ,  A61Q17/00 ,  A62D3/30 ,  A62D3/33 ,  A62D2101/02 ,  A62D2101/04 ,  A62D2101/22 ,  A62D2101/24 ,  A62D2101/26 ,  A62D2101/28 ,  A62D2101/43 ,  A62D2101/45 ,  A62D2101/47 ,  A62D2101/49

摘要： The present invention is directed to a formulation and associated method for neutralizing one or more toxic chemical and/or materials including toxic industrial chemicals and toxic industrial materials, such as irritants, heavy metals, radioactive metals, acids and acid irritants, pesticides, and various agricultural chemicals, (collectively referred to as toxic chemical, materials, or simply toxins) as well as decontaminating surfaces that have come into contact with these agents. As a result, the formulation of the present invention can be used for neutralizing a broad spectrum of toxic chemicals and materials. In one embodiment, the active ingredient comprises 2, 3, butanedione monoxime (also known as diacetyl monoxime (DAM)), and alkali salts thereof such as potassium 2,3-butanedione monoxime (KBDO). The formulation also typically includes a carrier in which the active ingredient is dispersed. In one embodiment, the carrier comprises polyethylene glycol (PEG); monomethoxypolyethylene glycol(mPEG); and combinations and derivatives thereof.

摘要翻译： 本发明涉及一种制剂，和用于中和一种或多种有毒化学品和/或材料，包括有毒工业化学品和有毒工业材料，颜色相关联的方法：如刺激剂，重金属，放射性金属，酸和酸刺激剂，杀虫剂和多种 农业化学品，（由统称为有毒化学品，物质或简单毒素），以及去污表面thathave成与合成剂接触。 其结果是，本发明的制剂可用于中和有毒化学品和材料的广谱。 在一个中，活性成分的实施例包括2,3-丁二酮单肟（因此称为二乙酰单肟（DAM）），以及它们的碱金属盐：如钾2,3-丁二酮单肟（KBDO）。 因此，配制剂通常包括其中活性成分分散的载体。 在一个实施方案中，载体包含聚乙二醇（PEG）; 单甲氧基聚乙二醇（mPEG）; 及其组合和衍生物。