专利检索 ap:("ELAN CORPORATION PLC" OR "CYTOGEN CORPORATION") AND inv:"SEVESO, Michela,Apartment 89" 第 1 页

1.

发明公开
PEPTIDES WHICH ENHANCE TRANSPORT OF AN ACTIVE AGENT ACROSS TISSUES AND COMPOSITIONS AND METHODS OF USING THE SAME 失效
标题翻译：肽，其活性物质通过织物上的运输及提高成份和方法使用相同的

公开(公告)号：EP0981649A1

公开(公告)日：2000-03-01

申请号：EP98923466.1

申请日：1998-05-15

申请人： ELAN CORPORATION PLC , CYTOGEN CORPORATION

发明人： O'MAHONY, Daniel, Joseph , ALVAREZ, Vernon, Leon , SEVESO, Michela,Apartment 89

IPC分类号： C12Q1/68 , C07K5/00

CPC分类号： C40B40/02 , A61K9/167 , A61K47/42 , A61K47/62 , A61K47/6937 , B82Y5/00 , C12N15/1037 , G01N33/68 , Y10S977/805

摘要： Targeting agents that are capable of permitting or facilitating transport of an active agent through a human or animal gastro-intestinal tissue. These targeting agents are peptides or their derivatives (e.g., fragments) and peptidomimetics thereof, and the nucleotide sequences coding for the peptides and derivatives. The targeting agents have use in facilitating transport of active agents from the lumenal side of the GIT into the systemic blood system, and/or in targeting active agents to the GIT. Therapeutic methods of administration, pharmaceutical compositions and formulations based on the targeting agent peptides are also provided. Preferably, the active agent is a drug or drug-containing nano- or microparticle.