-
公开(公告)号：EP1697304B1
公开(公告)日：2008-02-20
申请号：EP04820002.6
申请日：2004-11-16
发明人： CANADA, Emily, Jane , GOSSETT, Lynn, Stacy , MANTELO, Nathan, Bryan , SHI, Qing , WANG, Minmin , WARSHAWSKY, Alan, M. , XU, Yanping
IPC分类号： C07C233/73 , C07C271/16 , C07C311/04 , C07C317/44 , C07C323/62 , C07D209/42 , C07D209/46 , C07D213/81 , C07D217/06 , C07D333/70 , A61K31/166 , A61K31/265 , A61K31/18 , A61K31/381 , A61K31/4035
CPC分类号： C07D213/81 , C07C211/29 , C07C233/73 , C07C235/46 , C07C235/48 , C07C235/54 , C07C235/84 , C07C271/16 , C07C311/04 , C07C311/17 , C07C317/44 , C07C323/62 , C07D209/30 , C07D209/42 , C07D213/56 , C07D333/70
摘要： The present invention is directed to a compound of formula (I), or a pharmaceutically acceptable salt, solvate hydrate or stereoisomer thereof, which is useful in treating or preventing disorders mediated by a peroxisome proliferator activated receptor (PPAR) such as syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis, and other disorders related to syndrome X and cardiovascular diseases.
-
2.发明公开BICYCLIC SUBSTITUTED INDOLE-DERIVATIVE STEROID HORMONE NUCLEAR RECEPTOR MODULATORS 有权取代的类固醇激素，核受体的调节剂的双环吲哚衍生物
公开(公告)号：EP1723105A1
公开(公告)日：2006-11-22
申请号：EP05723294.4
申请日：2005-02-18
IPC分类号： C07D209/08 , C07D209/10 , C07D403/10 , C07D405/04 , C07D409/04 , C07D209/12 , C07D209/14 , A61K31/404 , A61P9/04 , A61P9/10 , A61P19/02 , A61P11/00
CPC分类号： C07D209/08 , C07D209/10 , C07D209/12 , C07D209/14 , C07D403/10 , C07D405/04 , C07D409/04
摘要： The present invention provides a compound of the formula: Formula (I); or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising an effective amount of a compound of Formula I in combination with a suitable carrier, diluent, or excipient, and methods for treating physiological disorders, particularly congestive heart disease, hypertension, and atherosclerosis, comprising administering to a patient in thereof an effective amount of a compound of Formula I. X-16125
-
3.发明授权BICYCLIC SUBSTITUTED INDOLE-DERIVATIVE STEROID HORMONE NUCLEAR RECEPTOR MODULATORS 有权取代的类固醇激素，核受体的调节剂的双环吲哚衍生物
公开(公告)号：EP1723105B1
公开(公告)日：2013-05-15
申请号：EP05723294.4
申请日：2005-02-18
IPC分类号： C07D209/08 , C07D209/10 , C07D403/10 , C07D405/04 , C07D409/04 , C07D209/12 , C07D209/14 , A61K31/404 , A61P9/04 , A61P9/10 , A61P19/02 , A61P11/00
CPC分类号： C07D209/08 , C07D209/10 , C07D209/12 , C07D209/14 , C07D403/10 , C07D405/04 , C07D409/04
-
公开(公告)号：EP1697304A1
公开(公告)日：2006-09-06
申请号：EP04820002.6
申请日：2004-11-16
发明人： CANADA, Emily, Jane , GOSSETT, Lynn, Stacy , MANTELO, Nathan, Bryan , SHI, Qing , WANG, Minmin , WARSHAWSKY, Alan, M. , XU, Yanping
IPC分类号： C07C233/73 , C07C271/16 , C07C311/04 , C07C317/44 , C07C323/62 , C07D209/42 , C07D209/46 , C07D213/81 , C07D217/06 , C07D333/70 , A61K31/166 , A61K31/265 , A61K31/18 , A61K31/381 , A61K31/4035
CPC分类号： C07D213/81 , C07C211/29 , C07C233/73 , C07C235/46 , C07C235/48 , C07C235/54 , C07C235/84 , C07C271/16 , C07C311/04 , C07C311/17 , C07C317/44 , C07C323/62 , C07D209/30 , C07D209/42 , C07D213/56 , C07D333/70
摘要： The present invention is directed to a compound of formula (I), or a pharmaceutically acceptable salt, solvate hydrate or stereoisomer thereof, which is useful in treating or preventing disorders mediated by a peroxisome proliferator activated receptor (PPAR) such as syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis, and other disorders related to syndrome X and cardiovascular diseases.
-
公开(公告)号：EP1660428A1
公开(公告)日：2006-05-31
申请号：EP04779442.5
申请日：2004-08-17
发明人： GONZALEZ VALCARCEL, Isabel, Cristina , MANTLO, Nathan, Bryan , SHI, Qing , WANG, Minmin , WINNEROSKI, Leonard, Larry, Junior , XU, Yanping , YORK, Jeremy, Schulenburg
IPC分类号： C07C59/68 , A61K31/095 , A61K31/185 , A61P3/04 , A61P3/10
CPC分类号： C07D213/30 , A61K31/095 , A61K31/185 , A61K45/06 , C07B2200/07 , C07C59/68 , C07C59/72 , C07C59/86 , C07C59/88 , C07C59/90 , C07C61/39 , C07C62/34 , C07C251/48 , C07C317/22 , C07C323/20 , C07C323/52 , C07C323/62 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07D213/69 , C07D239/26 , C07D261/20 , C07D263/32 , C07D277/24 , C07D307/79 , A61K2300/00
摘要： The present invention is directed to a compound of formula I, or a pharmaceutically acceptable salt, solvate, hydrate or stereoisomer thereof, which is useful in treating or preventing disorders mediated by a peroxisome proliferator activated receptor (PPAR) such as syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis, and other disorders related to syndrome X and cardiovascular diseases.
摘要翻译： 本发明涉及式I化合物或其药学上可接受的盐，溶剂合物，水合物或立体异构体，其可用于治疗或预防由过氧化物酶体增殖物激活受体（PPAR）介导的病症，例如综合征X，II型 糖尿病，高血糖症，高脂血症，肥胖，凝血病，高血压，动脉硬化以及与综合征X和心血管疾病相关的其它疾病。
-
-
-
-
搜索结果
5 条记录 (耗时 0.019 秒)
