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1.发明公开BIARYL-OXA(THIA)ZOLE DERIVATIVES AND THEIR USE AS PPARS MODULATORS 有权联芳OXA（THIA）ZOLDERIVATE及其作为调节剂PPARs的
公开(公告)号：EP1206457A1
公开(公告)日：2002-05-22
申请号：EP00959401.1
申请日：2000-08-23
发明人： BROOKS, Dawn A. , RITO, Christopher, J. , SHUKER, Anthony, J. , DOMINIANNI, Samuel, J. , WARSHAWSKY, Alan, M. , GOSSETT, Lynn, S. , MATTHEWS, Donald, P. , HAY, David, A. , ARDECKY, Robert, J. , MICHELLYS, Pierre-Yves , TYHONAS, John. S.
IPC分类号： C07D263/32 , C07D277/24 , C07D413/10 , A61K31/421 , A61K31/422 , A61K31/426 , A61K31/427 , A61K31/4439 , A61K31/506 , A61P3/10 , A61P9/00
CPC分类号： C07D413/10 , C07D263/32 , C07D277/24
摘要： Compounds represented by Formula (I) wherein n is 2, 3, or 4; V is O or S; W is O, S, or SO2 and at least one R5 is a substituted or unsubstituted aryl or a substituted or unsubstituted heteroaryl; are modulators of peroxisome proliferator activated receptors and are useful in the treatment of type II diabetes and of cardiovascular diseases.
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2.发明授权BIARYL-OXA(THIA)ZOLE DERIVATIVES AND THEIR USE AS PPARS MODULATORS 有权联芳OXA（THIA）ZOLDERIVATE及其作为调节剂PPARs的
公开(公告)号：EP1206457B1
公开(公告)日：2003-10-15
申请号：EP00959401.1
申请日：2000-08-23
发明人： BROOKS, Dawn A. , RITO, Christopher, J. , SHUKER, Anthony, J. , DOMINIANNI, Samuel, J. , WARSHAWSKY, Alan, M. , GOSSETT, Lynn, S. , MATTHEWS, Donald, P. , HAY, David, A. , ARDECKY, Robert, J. , MICHELLYS, Pierre-Yves , TYHONAS, John. S.
IPC分类号： C07D263/32 , C07D277/24 , C07D413/10 , A61K31/421 , A61K31/422 , A61K31/426 , A61K31/427 , A61K31/4439 , A61K31/506 , A61P3/10 , A61P9/00
CPC分类号： C07D413/10 , C07D263/32 , C07D277/24
摘要： Compounds represented by Formula (I) wherein n is 2, 3, or 4; V is O or S; W is O, S, or SO2 and at least one R5 is a substituted or unsubstituted aryl or a substituted or unsubstituted heteroaryl; are modulators of peroxisome proliferator activated receptors and are useful in the treatment of type II diabetes and of cardiovascular diseases.
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