公开(公告)号：EP2675462A2

公开(公告)日：2013-12-25

申请号：EP12702582.3

申请日：2012-01-03

申请人： Elicityl ,  Centre National de la Recherche Scientifique ,  Institut National de la Santé et de la Recherche Médicale ,  Commissariat à l'Énergie Atomique et aux Énergies Alternatives

发明人： LINA, Bruno ,  FERRARIS, Olivier ,  VO, Ho Hong Hai ,  COSSET, François-Loïc ,  SZECSI, Judit ,  HEYRAUD, Alain ,  LORTAT-JACOB, Hugues ,  BARTOLI, Julia ,  SADIR, Rabia ,  LIVACHE, Thierry ,  DARBLADE, Benoît ,  HAVET, Stéphane ,  BONNET, Silvère

IPC分类号： A61K31/715

CPC分类号： A61K31/737 ,  A61K31/715 ,  A61K36/05 ,  A61K36/888

摘要： The present invention relates to polysaccharides selected from sulphated arabinogalactans, apiogalacturonans and sulphated heteroglycans intended to be used as a drug for the preventive or curative treatment of an influenza virus, as well as to the pharmaceutical compositions including, in particular in combination with at least one pharmaceutically acceptable carrier: either an extract of Codium fragile, including sulphated arabinogalactans, or an extract of Zostera marina or Lemna minor, including apiogalacturonans, or an extract of Caulerpa racemosa, including sulphated heteroglycans.

摘要翻译： 本发明涉及从硫酸化阿拉伯半乳聚糖，apiogalacturonans和硫酸杂多糖的旨在被用作用于流感病毒的预防性或治疗性治疗的药物，以及对所述药物组合物，包括选择的多糖，particulare组合与至少一种 药学上可接受的载体：其中之一来提取刺松的脆弱，包括硫酸化阿拉伯半乳聚糖，或以提取叶藻或青萍，包括apiogalacturonans的，或以提取总状蕨藻，包括硫酸化杂多糖。

公开(公告)号：EP3291906A1

公开(公告)日：2018-03-14

申请号：EP16729010.5

申请日：2016-05-03

申请人： Elicityl ,  Research Foundation For Medical Devices

发明人： BASTIDE, Ludovic ,  BONNET, Silvère ,  DARBLADE, Benoît ,  HAVET, Stéphane ,  MANDRAND, Bernard ,  RANDRIANTSOA, Mialy ,  ZERIS, Jean-Philippe

IPC分类号： B01D15/38 ,  A61M1/36

CPC分类号： B01J20/3212 ,  A61K35/16 ,  A61M1/0281 ,  A61M1/3679 ,  B01D15/3804 ,  B01D15/3809 ,  B01J20/286 ,  B01J20/3219 ,  B01J20/3274 ,  B01J20/3278 ,  G01N33/491

摘要： The invention relates to a method for the purification of a body fluid comprising antibodies corresponding to whole human or animal blood or to a product derived from human or animal blood, in which the body fluid is brought into contact with at least one substrate comprising a solid phase to which molecules of at least one oligosaccharide that can bind to one or more antibodies present in the body fluid are covalently grafted, such as to capture at least a portion of the antibodies present in the body fluid by means of bond(s) with at least some of the oligosaccharide molecules grafted to the solid phase. The method is characterised in that the solid phase carries free aldehyde (-CHO) functions.

公开(公告)号：EP3291905A1

公开(公告)日：2018-03-14

申请号：EP16727750.8

申请日：2016-05-03

申请人： Elicityl

发明人： BASTIDE, Ludovic ,  BONNET, Silvère ,  DARBLADE, Benoît ,  HAVET, Stéphane ,  MANDRAND, Bernard ,  RANDRIANTSOA, Mialy

IPC分类号： B01D15/38 ,  B01J20/24 ,  B01J20/286 ,  B01J20/32 ,  A61M1/36 ,  G01N33/49

CPC分类号： B01J20/289 ,  A61M1/3679 ,  A61M2202/0413 ,  B01D15/3804 ,  B01D15/3809 ,  B01J20/223 ,  B01J20/24 ,  B01J20/286 ,  B01J20/288 ,  B01J20/3208 ,  B01J20/3212 ,  B01J20/3219 ,  B01J20/3244 ,  B01J20/3274 ,  B01J20/3278 ,  G01N33/491

摘要： The invention relates to a substrate for the purification of a body fluid, comprising a solid phase to which molecules of at least one oligosaccharide that can bind to one or more antibodies are covalently grafted, said solid phase carrying free aldehyde (-CHO) functions. The invention also relates to a method for producing such a substrate, the use of such a substrate in stabilising the antibody/oligosaccharide bond, and a method for purifying a body fluid, in which the body fluid is brought into contact with at least one substrate according to the invention, such as to capture antibodies present in the body fluid by means of bond(s) with at least some of the oligosaccharide molecules grafted to the solid phase.