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1.发明授权
公开(公告)号：EP1622896B1
公开(公告)日：2007-07-04
申请号：EP04730211.2
申请日：2004-04-29
IPC分类号： C07D413/12 , A61K31/422 , A61P35/00
CPC分类号： C07D413/12 , C07D413/14
摘要： Objects of the present invention are the compounds of formula (I) their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
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2.发明公开
公开(公告)号：EP1613623A1
公开(公告)日：2006-01-11
申请号：EP04723580.9
申请日：2004-03-26
发明人： BOSSENMAIER, Birgit , FRIEBE, Walter-Gunar , FRIESS, Thomas , GOLLER, Bernhard , RUETH, Matthias , VOSS, Edgar
IPC分类号： C07D413/12 , C07D413/14 , A61K31/422 , A61P35/00
CPC分类号： C07D413/12 , C07D413/14
摘要： Object of the present invention are compounds of the general formla (1), their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
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3.发明公开
公开(公告)号：EP1622896A1
公开(公告)日：2006-02-08
申请号：EP04730211.2
申请日：2004-04-29
IPC分类号： C07D413/12 , A61K31/422 , A61P35/00
CPC分类号： C07D413/12 , C07D413/14
摘要： Objects of the present invention are the compounds of formula (I) their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
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公开(公告)号：EP1487819A2
公开(公告)日：2004-12-22
申请号：EP03711955.9
申请日：2003-03-10
IPC分类号： C07D401/12 , A61K31/55 , A61P35/00 , C07D401/14 , C07D405/14 , C07D403/12
CPC分类号： C07D401/12 , C07D223/12 , C07D401/14 , C07D403/12 , C07D405/14
摘要： This invention provides novel azepane derivatives or pharmaceutically acceptable salts thereof, according to the general formula ( I ) wherein the remaining symbols have the significance given in the specification, as well as processes for their manufacture. The compounds according to this invention possess anti-cell proliferation activity and show an increased plasma-stability.
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5.发明公开THIAZOLIDINE CARBOXYLIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER 审中-公开THIAZOLIDINCARBONSÄUREDERIVATE及其用于癌症治疗
公开(公告)号：EP1189894A1
公开(公告)日：2002-03-27
申请号：EP01902357.1
申请日：2001-01-27
IPC分类号： C07D277/20 , C07D417/12 , A61K31/426 , A61P35/00
CPC分类号： C07D277/20 , C07D417/12 , C07D417/14
摘要： 5-Arylidene-4-oxo-2-thioxo-3-thiazolidinecarboxylic acids of formula (I) in which the symbols R?1, R2, A, A1 and A2¿ have the significance given in the description as medicaments for the treatment of cancer diseases.
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6.发明公开1-'(E)-2-(PHENYL)ETHENYL-4-(ARYLALKOXY)-OXAZOLE OR -THIAZOLE COMPOUNDS AS HER-2 TYROSINE KINASES INHIBITORS AND THEIR USE IN THE TREATMENT OF CANCER 审中-公开1“ - （E）-2-（苯基）乙烯基-4-（芳基烷氧基）恶唑或-THIAZOLVERBINDUNGEN如HER-2酪氨酸激酶的抑制剂以及它们在癌症的治疗中使用
公开(公告)号：EP1680417A1
公开(公告)日：2006-07-19
申请号：EP04790740.7
申请日：2004-10-22
IPC分类号： C07D413/14 , C07D417/14 , A61K31/426 , A61K31/4192 , A61K31/422 , A61K31/4155 , A61P35/00
CPC分类号： C07D417/14 , C07D413/14
摘要： Objects of the present invention are the compounds of formula (I), their pharmaceutically acceptable salts, enantiomeric forms thereof, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
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公开(公告)号：EP1656371A2
公开(公告)日：2006-05-17
申请号：EP04764040.4
申请日：2004-08-12
IPC分类号： C07D413/12 , A61K31/422
CPC分类号： C07D413/12
摘要： Objects of the present invention are compounds of formula (I) formula (I), their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
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