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    REDOXINDICATORS
    3.
    发明公开
    REDOXINDICATORS 审中-公开

    公开(公告)号：EP3183246A1

    公开(公告)日：2017-06-28

    申请号：EP15753944.6

    申请日：2015-08-21

    申请人： Roche Diagnostics GmbH ,  F. Hoffmann-La Roche AG

    发明人： GEBAUER, Peter ,  HEINDL, Dieter ,  HORN, Carina ,  FOMIN, Maksim

    IPC分类号： C07D401/06 ,  C07D241/40

    摘要： The present invention relates to a chemical compound or a salt or solvate thereof being a phenazine-, phenanthridine-, phenanthroline-, quinoline-, quinoxaline-, acridine-isoquinoline-, pyrazine- or pyridine-derivative comprising a conjugated π-system and a π-acceptor group, and to uses thereof. The present invention further relates to a chemistry matrix and to a test element comprising the chemical compound of the present invention. The present invention also relates to a method of determining the amount of an analyte in a test sample, comprising contacting said test sample with a chemical compound, with a chemistry matrix, or with a test element of the invention and estimating the amount of redox equivalents liberated or consumed by the chemical compound, by the chemical compound comprised in said chemistry matrix, or by the chemical compound comprised in said test element, in the presence of said test sample, thereby determining the amount of an analyte in said test sample. Moreover, the present invention relates to a system comprising a test element according to the present invention and a device comprising a sensor for measuring the amount of redox equivalents liberated or consumed.

    摘要翻译： 本发明涉及一种化合物或其盐或溶剂化物，其是包含共轭π-系统的吩嗪 - ，菲啶 - ，菲咯啉 - ，喹啉 - ，喹喔啉 - ，吖啶 - 异喹啉 - ，吡嗪 - 或吡啶 - π-受体基团，以及其用途。 本发明进一步涉及化学基质和包含本发明化学化合物的测试元件。 本发明还涉及确定测试样品中分析物的量的方法，其包括使所述测试样品与化学化合物，化学基质或本发明的测试元件接触并估计氧化还原当量的量 由所述化学基质中包含的化学化合物释放或消耗，或者在所述测试样品存在下由所述测试元件中包含的化学化合物释放或消耗，从而确定所述测试样品中分析物的量。 此外，本发明涉及包括根据本发明的测试元件的系统和包括用于测量释放或消耗的氧化还原当量的量的传感器的装置。