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公开(公告)号：EP4360646A2
公开(公告)日：2024-05-01
申请号：EP23209560.4
申请日：2016-09-23
发明人： GROGAN, Jane L. , JOHNSTON, Robert J. , WU, Yan , LIANG, Wei-Ching , LUPARDUS, Patrick , YADAV, Mahesh , SESHASAYEE, Dhaya , HAZEN, Meredith
IPC分类号： A61K39/00
CPC分类号： A61K2039/50520130101 , C07K2317/3320130101 , C07K2317/3420130101 , C07K2317/7020130101 , C07K2317/9020130101 , C07K16/28 , A61K38/177 , C07K2317/9220130101 , C07K2317/7620130101 , C07K2317/9420130101 , A61P31/00 , A61P35/00 , A61P35/02 , A61P37/00 , A61P37/02 , A61P37/04 , A61P43/00 , Y02A50/30
摘要： The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号：EP4360646A3
公开(公告)日：2024-05-15
申请号：EP23209560.4
申请日：2016-09-23
发明人： GROGAN, Jane L. , JOHNSTON, Robert J. , WU, Yan , LIANG, Wei-Ching , LUPARDUS, Patrick , YADAV, Mahesh , SESHASAYEE, Dhaya , HAZEN, Meredith
IPC分类号： C07K16/28 , A61K39/00 , A61K38/17 , A61P31/00 , A61P35/00 , A61P35/02 , A61P37/00 , A61P37/02 , A61P37/04 , A61P43/00
CPC分类号： A61K2039/50520130101 , C07K2317/3320130101 , C07K2317/3420130101 , C07K2317/7020130101 , C07K2317/9020130101 , C07K16/28 , A61K38/177 , C07K2317/9220130101 , C07K2317/7620130101 , C07K2317/9420130101 , A61P31/00 , A61P35/00 , A61P35/02 , A61P37/00 , A61P37/02 , A61P37/04 , A61P43/00 , Y02A50/30
摘要： The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号：EP3194970A1
公开(公告)日：2017-07-26
申请号：EP15772084.8
申请日：2015-09-10
发明人： DELAMARRE, Lelia , LUPARDUS, Patrick , MELLMAN, Ira , YADAV, Mahesh , JHUNJHUNWALA, Suchit , LILL, Jennie
IPC分类号： G01N33/569 , A61K39/00 , C12Q1/68 , G01N33/68
CPC分类号： G01N33/6848 , A61K39/00 , A61K39/0011 , A61K2039/55516 , A61K2039/55561 , C12Q1/6886 , C12Q2600/156 , G01N33/56977 , G01N33/6878 , G01N2333/70539 , G01N2800/7028
摘要： The present disclosure provides methods of identifying a disease-specific immunogenic peptide through a series of selection steps. Immunogenic epitopes identified by methods of the present disclosure are applicable for use in peptide-based immunotherapy, preferably cancer therapy. Furthermore, the methods of the present disclosure may be performed in a high-throughput manner and serve as a means of personalized vaccine development and therapy. Also provided are compositions of immunogenic peptides as well as methods of treatment comprising said compositions.
摘要翻译： 本公开提供了通过一系列选择步骤鉴定疾病特异性免疫原性肽的方法。 通过本公开的方法鉴定的免疫原性表位适用于基于肽的免疫疗法，优选癌症疗法。 此外，本公开的方法可以以高通量方式进行并且用作个性化疫苗开发和治疗的手段。 还提供了免疫原性肽的组合物以及包含所述组合物的治疗方法。
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4.发明公开
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公开(公告)号：EP3998481A1
公开(公告)日：2022-05-18
申请号：EP21187832.7
申请日：2015-09-10
发明人： DELAMARRE, Lelia , LUPARDUS, Patrick , MELLMAN, Ira , YADAV, Mahesh , JHUNJHUNWALA, Suchit , LILL, Jennie
IPC分类号： G01N33/68
摘要： The present disclosure provides methods of identifying a disease-specific immunogenic peptide through a series of selection steps. Immunogenic epitopes identified by methods of the present disclosure are applicable for use in peptide-based immunotherapy, preferably cancer therapy. Furthermore, the methods of the present disclosure may be performed in a high-throughput manner and serve as a means of personalized vaccine development and therapy. Also provided are compositions of immunogenic peptides as well as methods of treatment comprising said compositions.
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公开(公告)号：EP3353210A2
公开(公告)日：2018-08-01
申请号：EP16775058.7
申请日：2016-09-23
发明人： GROGAN, Jane, L. , JOHNSTON, Robert, J. , WU, Yan , LIANG, Wei-Ching , LUPARDUS, Patrick , YADAV, Mahesh , SESHASAYEE, Dhaya , HAZEN, Meredith
CPC分类号： C07K16/28 , A61K38/177 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/2818 , C07K16/2827 , C07K16/2878 , C07K16/3061 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/567 , C07K2317/70 , C07K2317/75 , C07K2317/76 , C07K2317/90 , C07K2317/92 , C07K2317/94 , Y02A50/466
摘要： The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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