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公开(公告)号:EP4351577A1
公开(公告)日:2024-04-17
申请号:EP22732509.9
申请日:2022-06-07
发明人: ECKMANN, Jan , FRIESS, Thomas , HERTING, Frank , IDE, Yusuke , TANAKA, Hiroshi , PETTAZZONI, Piergiorgio Francesco Tommaso , WICHMANN, Juergen
IPC分类号: A61K31/495 , A61K31/4184 , A61K31/4523 , A61K45/06 , A61P35/00 , A61K31/502 , A61K31/44 , A61K31/517
CPC分类号: A61K45/06 , A61P35/00 , A61K31/4523 , A61K31/4184 , A61K31/44 , A61K31/517
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公开(公告)号:EP3383173B1
公开(公告)日:2020-11-25
申请号:EP16802036.0
申请日:2016-11-28
发明人: ECKMANN, Jan , HOVES, Sabine , RIES, Carola
IPC分类号: A01K67/027 , C12N5/0786 , A61K39/395 , C07K16/28
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公开(公告)号:EP3383173A1
公开(公告)日:2018-10-10
申请号:EP16802036.0
申请日:2016-11-28
发明人: ECKMANN, Jan , HOVES, Sabine , RIES, Carola
IPC分类号: A01K67/027 , C12N5/0786 , A61K39/395 , C07K16/28
CPC分类号: C07K16/2866 , A01K67/0271 , A01K2207/10 , A01K2207/12 , A01K2207/15 , A01K2267/0331 , A01K2267/0381 , A61K39/395 , A61K2039/505 , C12N5/0645 , C12N2501/22 , G01N33/50
摘要: The invention relates to the use of non-anti-human antibodies to stimulate the generation of human macrophages in immunodeficient non-human hosts, reconstituted with human immune system. According methods for the generation and host models with human xenografts as well as their use for cancer immunotherapy evaluation are also included.
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公开(公告)号:EP4396230A1
公开(公告)日:2024-07-10
申请号:EP22776886.8
申请日:2022-09-02
发明人: AMANN, Maria , POUSSE, Laurène , BOETSCH, Christophe , WEISSER, Martin , KOLBEN, Theresa , KARANIKAS, Vaios , ECKMANN, Jan , CARNEIRO DE MEDEIROS, Bruno
IPC分类号: C07K16/28 , A61P35/02 , A61P35/00 , A61K39/395 , A61K39/00
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公开(公告)号:EP4351582A1
公开(公告)日:2024-04-17
申请号:EP22733341.6
申请日:2022-06-07
发明人: ECKMANN, Jan , FRIESS, Thomas , HERTING, Frank , PETTAZZONI, Piergiorgio Francesco Tommaso , WICHMANN, Juergen
IPC分类号: A61K31/517 , A61K39/395 , A61K45/06 , A61P35/00
CPC分类号: A61K31/517 , A61K39/395 , A61K45/06 , A61P35/00 , C07K16/2818
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