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1.发明公开2-STYRYL-4-OXAZOLE-METHANOL-ETHERS AND THEIR USE AS TYROSINE KINASE INHIBITORS 审中-公开2-苯乙烯基-4- OXAZOLMETHANOLETHER及其作为酪氨酸激酶抑制剂的应用
公开(公告)号：EP1756097A1
公开(公告)日：2007-02-28
申请号：EP05746504.9
申请日：2005-05-24
发明人： BOSSENMAIER, Birgit , FRIEBE, Walter-Gunar , FRIESS, Thomas , GELETNEKY, Christian , GEORGES, Guy , KOLM, Irene , VOSS, Edgar
IPC分类号： C07D413/12 , A61K31/422 , A61P35/00
CPC分类号： C07D249/08 , C07D231/12 , C07D233/56 , C07D413/12
摘要： Objects of the present invention are the compounds of formula (I), their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
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2.发明公开
公开(公告)号：EP1848713A2
公开(公告)日：2007-10-31
申请号：EP05816600.0
申请日：2005-11-21
发明人： BOSSENMAIER, Birgit , FRIEBE, Walter-Gunar , HOFFMANN, Eike , VON HIRSCHHEYDT, Thomas , VOSS, Edgar
IPC分类号： C07D413/14
CPC分类号： C07D413/14 , C07D409/12 , C07D413/12 , C07D417/12 , C07D417/14
摘要： Objects of the present invention are the compounds of formula (I), their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
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公开(公告)号：EP1761525B1
公开(公告)日：2008-07-23
申请号：EP05750944.0
申请日：2005-05-24
发明人： BOSSENMAIER, Birgit , FRIEBE, Walter-Gunar , FRIESS, Thomas , KLING, Lothar , REIFF, Ulrike , VOSS, Edgar
IPC分类号： C07D413/12 , A61K31/422 , A61P35/00
CPC分类号： C07D413/12
摘要： Objects of the present invention are the compounds of formula (I), their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
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4.发明公开PYRAZOLE DERIVATIVES, THEIR MANUFACTURE AND THEIR USE AS PHARMACEUTICAL AGENTS 审中-公开吡唑衍生物，其制备方法及其作为药剂
公开(公告)号：EP1915370A1
公开(公告)日：2008-04-30
申请号：EP06776646.9
申请日：2006-08-07
IPC分类号： C07D413/12 , A61K31/422 , A61P35/00
CPC分类号： C07D413/12
摘要： Objects of the present invention are the compounds of formula (I), their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
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公开(公告)号：EP1727815B1
公开(公告)日：2007-06-27
申请号：EP05716141.6
申请日：2005-03-17
IPC分类号： C07D413/12 , C07D417/12 , C07D413/14 , A61K31/422 , A61K31/427
CPC分类号： C07D417/12 , C07D413/12 , C07D413/14
摘要： Objects of the present invention are the compounds of Formula (I), their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
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公开(公告)号：EP1737846A1
公开(公告)日：2007-01-03
申请号：EP05716459.2
申请日：2005-03-31
IPC分类号： C07D403/06
CPC分类号： C07D413/14
摘要： The invention relates to a new process for the preparation of pyrazine derivatives of formula (I), which are useful as intermediates for the preparation of liquid crystalline media components or of pharmaceutically active substances.
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公开(公告)号：EP1727815A1
公开(公告)日：2006-12-06
申请号：EP05716141.6
申请日：2005-03-17
IPC分类号： C07D413/12 , C07D417/12 , C07D413/14 , A61K31/422 , A61K31/427
CPC分类号： C07D417/12 , C07D413/12 , C07D413/14
摘要： Objects of the present invention are the compounds of Formula (I), their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
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8.发明公开PENTAFLUOROSULFANYL COMPOUNDS, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS 审中-公开PENTAFLUORSULFANYLVERBINDUNGEN，生产和使用作为药剂
公开(公告)号：EP1725549A1
公开(公告)日：2006-11-29
申请号：EP05715739.8
申请日：2005-03-04
IPC分类号： C07D413/10 , C07D413/12 , A61K31/41 , A61P35/00 , C07D263/00 , C07D249/00 , C07D257/00 , C07D233/00
CPC分类号： C07D413/12 , C07D413/10
摘要： Objects of the present invention are the compounds of formula I-A (I), their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
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9.发明公开
公开(公告)号：EP1912969A1
公开(公告)日：2008-04-23
申请号：EP06776560.2
申请日：2006-08-02
发明人： BOSSENMAIER, Birgit , FRIESS, Thomas , JUCHEM, Rolf , KLING, Lothar , KOLM, Irene , KRELL, Hans-Willi , VON HIRSCHHEYDT, Thomas , VOSS, Edgar
IPC分类号： C07D401/12 , A61K31/4439 , A61P35/02
CPC分类号： C07D401/12
摘要： Objects of the present invention are the compounds of formula (I) their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
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公开(公告)号：EP1761525A1
公开(公告)日：2007-03-14
申请号：EP05750944.0
申请日：2005-05-24
发明人： BOSSENMAIER, Birgit , FRIEBE, Walter-Gunar , FRIESS, Thomas , KLING, Lothar , REIFF, Ulrike , VOSS, Edgar
IPC分类号： C07D413/12 , A61K31/422 , A61P35/00 , C07D263/00 , C07D249/00
CPC分类号： C07D413/12
摘要： Objects of the present invention are the compounds of formula (I), their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
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