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公开(公告)号:EP3086807A1
公开(公告)日:2016-11-02
申请号:EP14827379.0
申请日:2014-12-23
发明人: CHEN, Yongmei , ERNST, James , KIM, Hok Seon , SONODA, Junichiro , SPIESS, Christoph , STAWICKI, Scott , WU, Yan
IPC分类号: A61K39/395 , C07K14/71 , C07K16/18 , C07K16/28 , C07K16/46
CPC分类号: C07K16/40 , A61K2039/505 , C07K14/71 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/40 , C07K2317/41 , C07K2317/51 , C07K2317/515 , C07K2317/524 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/71 , C07K2317/75 , C07K2317/92
摘要: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
摘要翻译: 目前公开的主题提供了结合KLB和FGFR1的抗体及其使用方法。 在某些实施方案中,本公开的抗体包括结合存在于FGFR1上并与KLB上存在的表位结合的双特异性抗体。
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公开(公告)号:EP3057615A2
公开(公告)日:2016-08-24
申请号:EP14790974.1
申请日:2014-10-17
发明人: STORM, Elaine , DE SAUVAGE, Frederic J. , MURRAY, Jeremy M. , NOLAND, Cameron L. , WU, Yan , TAN, Christine , HONGO, Jo-Anne , CHEN, Yongmei
IPC分类号: A61K39/395 , C07K16/18 , C07K16/28 , C07K16/30 , G01N33/574 , A61K39/00
CPC分类号: C07K16/18 , A61K39/3955 , A61K45/06 , A61K47/6843 , A61K2039/505 , C07K16/2818 , C07K16/3046 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/75 , C07K2317/76 , C07K2317/92
摘要: Provided herein are anti-RSPO antibodies, in particular anti-RSPO2 antibodies and/or anti-RSPO3 antibodies, and methods of using the same.
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公开(公告)号:EP2638070A1
公开(公告)日:2013-09-18
申请号:EP11785551.0
申请日:2011-11-09
发明人: ATWAL, Jasvinder , CHEN, Yongmei , CHIU, Cecilia Pui Chi , LAZARUS, Robert A. , WANG, Weiru , WATTS, Ryan J. , WU, Yan , ZHANG, Yingnan
IPC分类号: C07K16/40 , G01N33/577 , A61K39/395 , A61P25/28
CPC分类号: C07K16/40 , A61K39/3955 , A61K47/6871 , A61K2039/505 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C12P21/005 , G01N33/573
摘要: The invention provides antibodies to specific neural proteins and methods of using the same.
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公开(公告)号:EP2638070B1
公开(公告)日:2016-10-19
申请号:EP11785551.0
申请日:2011-11-09
发明人: ATWAL, Jasvinder , CHEN, Yongmei , CHIU, Cecilia Pui Chi , LAZARUS, Robert A. , WANG, Weiru , WATTS, Ryan J. , WU, Yan , ZHANG, Yingnan
IPC分类号: C07K16/40 , G01N33/577 , A61K39/395 , A61P25/28
CPC分类号: C07K16/40 , A61K39/3955 , A61K47/6871 , A61K2039/505 , C07K2317/51 , C07K2317/515 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C12P21/005 , G01N33/573
摘要: The invention provides antibodies to specific neural proteins and methods of using the same.
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5.CROSS-REACTIVE AND BISPECIFIC ANTI-EL 17A/F ANTIBODIES 审中-公开
标题翻译: BISPEZIFISCHE ANTI-EL 17A / F-ANTIKÖRPER的KREUZREAKTIVE公开(公告)号:EP2321349A2
公开(公告)日:2011-05-18
申请号:EP09792076.3
申请日:2009-08-28
发明人: CHEN, Yongmei , HU, Yan (helen) , OUYANG, Wenjun , STAWICKI, Scott , WU, Yan
IPC分类号: C07K16/24 , A61K39/395
CPC分类号: C07K16/244 , C07K2317/31 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/92
摘要: The present invention relates generally to antibodies cross-reactive with IL- 17A and IL-17F, and bispecific anti-IL-17A/F and their uses.
摘要翻译: 本发明一般涉及与IL-17A和IL-17F交叉反应的抗体,以及双特异性抗IL-17A / F及其用途。
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