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1.发明公开METHODS OF TREATING HER2-POSITIVE CANCERS USING PD-1 AXIS BINDING ANTAGONISTS AND ANTI-HER2 ANTIBODIES 审中-公开METHOD FOR HER-2阳性的癌症与PD-1结合拮抗剂和抗HER2抗体治疗
公开(公告)号：EP3083692A1
公开(公告)日：2016-10-26
申请号：EP14833308.1
申请日：2014-12-17
发明人： DENNIS, Mark S. , EBENS, Allen , IRVING, Bryan , JUNTTILA, Teemu T. , LI, Ji
IPC分类号： C07K16/28 , A61K31/337
摘要： The invention provides methods and compositions for treating cancer and for enhancing immune function in an individual having cancer. The methods comprise administering a PD-1 axis binding antagonist and a taxane.
摘要翻译： 本发明提供了用于治疗癌症和用于增强个体在患有癌症的免疫功能的方法和组合物。 所述方法包括施用PD-1轴结合拮抗剂和紫杉烷。
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公开(公告)号：EP2414399A1
公开(公告)日：2012-02-08
申请号：EP10722862.9
申请日：2010-03-31
发明人： ELKINS, Kristi , POLSON, Andrew , EBENS, Allen , ADAMS, Camelia , ZHENG, Bing , JUNUTULA, Jagath, R. , HONGO, Jo-anne , WU, Yan
IPC分类号： C07K16/28 , A61K39/395 , A61P35/02 , C12N15/13 , C12N5/20 , C07K19/00 , G01N33/574
CPC分类号： G01N33/6854 , A61K31/138 , A61K31/4196 , A61K31/454 , A61K31/4745 , A61K31/517 , A61K31/56 , A61K31/568 , A61K31/5685 , A61K31/69 , A61K33/24 , A61K38/19 , A61K39/0011 , A61K39/39533 , A61K39/39558 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K16/2803 , C07K16/283 , C07K2317/24 , C07K2317/522 , C07K2317/73 , G01N33/574 , G01N33/6857 , Y02A50/473
摘要： The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号：EP2414395A1
公开(公告)日：2012-02-08
申请号：EP10711526.3
申请日：2010-03-31
发明人： ELKINS, Kristi , POLSON, Andrew , EBENS, Allen , ADAMS, Camelia , ZHENG, Bing , JUNUTULA, Jagath, R. , HONGO, Jo-anne , WU, Yan
IPC分类号： C07K16/28 , A61K39/395 , A61P35/02 , C12N15/13 , C12N5/20 , C07K19/00 , G01N33/574
CPC分类号： A61K39/3955 , A61K31/69 , A61K39/395 , A61K45/06 , A61K2039/505 , C07K16/283 , C07K2317/24 , C07K2317/92 , A61K2300/00
摘要： The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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