公开(公告)号：EP1962959B1

公开(公告)日：2012-03-14

申请号：EP06830133.2

申请日：2006-11-27

申请人： F.Hoffmann-La Roche AG

发明人： CONDE-KNAPE, Karin ,  DANHO, Waleed ,  EHRLICH, George ,  FOTOUHI, Nader ,  FRY, David C. ,  KHAN, Wajiha ,  KONKAR, Anish ,  RONDINONE, Cristina Martha ,  SWISTOK, Joseph ,  TAUB, Rebecca Anne ,  TILLEY, Jefferson W.

IPC分类号： C07K14/575 ,  A61K38/10 ,  A61K38/00

CPC分类号： C07K14/57545 ,  A61K38/00 ,  A61K47/60

摘要： Provided herein are neuropeptide-2 receptor agonists of the formula (I): as well as pharmaceutically acceptable salts, derivatives and fragments thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity and diabetes.

公开(公告)号：EP1962959A2

公开(公告)日：2008-09-03

申请号：EP06830133.2

申请日：2006-11-27

申请人： F.HOFFMANN-LA ROCHE AG

发明人： CONDE-KNAPE, Karin ,  DANHO, Waleed ,  EHRLICH, George ,  FOTOUHI, Nader ,  FRY, David C. ,  KHAN, Wajiha ,  KONKAR, Anish ,  RONDINONE, Cristina Martha ,  SWISTOK, Joseph ,  TAUB, Rebecca Anne ,  TILLEY, Jefferson W.

IPC分类号： A61P3/10

CPC分类号： C07K14/57545 ,  A61K38/00 ,  A61K47/60

摘要： Provided herein are neuropeptide-2 receptor agonists of the formula (I): as well as pharmaceutically acceptable salts, derivatives and fragments thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity and diabetes.