公开(公告)号：EP2953700A4

公开(公告)日：2017-02-15

申请号：EP14749278

申请日：2014-02-07

申请人： FLODESIGN SONICS INC

发明人： LIPKENS BART ,  MASI LOUIS ,  KOWALSKI III STANLEY ,  PRESZ WALTER M JR ,  DIONNE JASON ,  DUTRA BRIAN ,  MERCADO ARI ,  KENNEDY III THOMAS ,  MARTIN ARTHUR

IPC分类号： B01D17/04 ,  C02F1/36 ,  C02F1/40

CPC分类号： C12M47/06 ,  B01D21/283 ,  C12M29/10 ,  C12M33/08 ,  C12M47/02

摘要： A perfusion bioreactor includes at least one ultrasonic transducer that can acoustically generate a multi-dimensional standing wave. The standing wave can be used to retain cells in the bioreactor, and can also be utilized to dewater or further harvest product from the waste materials produced in a bioreactor. The bioreactor includes a reaction vessel, an agitator, a feed inlet, and an outlet. A filtering device is included that has an inlet, a flow chamber and a sleeve surrounding the flow chamber, where the sleeve includes the ultrasonic transducer.