-
1.发明公开New peptide, process for its preparation and pharmaceutical composition containing it 失效Neues Peptid，Verfahren zu dessen Herstellung und pharmazeutische Zusammensetzung。
公开(公告)号：EP0050856A2
公开(公告)日：1982-05-05
申请号：EP81108796.4
申请日：1981-10-23
发明人： Kitaura, Yoshihiko , Nakaguchi, Osamu , Hemmi, Keiji , Aratani, Matsuhiko , Takeno, Hidekazu , Okada, Satoshi , Tanaka, Hirokazu , Hashimoto, Masashi , Kuroda, Yoshio , Iguchi, Eiko , Kohsaka, Masanobu , Aoki, Hatsuo , Imanaka, Hiroshi
IPC分类号： C07C103/52 , C07H15/04 , A61K37/02
CPC分类号： C07C243/00 , A61K38/00 , C07K5/0215 , C07K9/005
摘要： A compound of the formula or its pharmaceutically acceptable salt:
where, in one example. R' is n-octanoyl, n is the integer O, R 2 is benzyl, R 3 is 1-carboxyethylammo, R 4 is hydrogen and R 5 is hydrogen and processes for their preparation and also a pharmaceutically composition comprising, as an effective ingredient, the above compound in association with pharmaceutically acceptable carriers.摘要翻译： 下式化合物或其药学上可接受的盐：
其中，在一个实例中，R 1为正辛酰基，n为整数O，R 2为苄基，R 3为1-羧乙基氨基，R 4为氢，R <5>是氢并且其制备方法以及药学组合物，其包含作为有效成分的上述化合物与药学上可接受的载体。 -
2.发明授权
公开(公告)号：EP0025842B1
公开(公告)日：1987-06-03
申请号：EP80104502.2
申请日：1980-07-30
发明人： Kitaura, Yoshihiko , Nakaguchi, Osamu , Hemmi, Keiji , Aratani, Matsuhiko , Takeno, Hidekazu , Okada, Satoshi , Tanaka, Hirokazu , Hashimoto, Masashi , Kuroda, Yoshio , Iguchi, Eiko , Kohsaka, Masanobu , Aoki, Hatsuo , Imanaka, Hiroshi
IPC分类号： C07K7/00 , C07H15/04 , C07H15/18 , A61K37/02 , C07C103/50 , C07C125/065
CPC分类号： C07C243/00 , A61K38/00 , C07K5/0215 , C07K9/005 , C12R1/465 , Y02P20/55
-
3.发明公开Peptides, process for their preparation, their pharmaceutical compositions and their intermediates 失效肽，其制备方法，其药物组合物和它们的中间体的过程。
公开(公告)号：EP0025842A2
公开(公告)日：1981-04-01
申请号：EP80104502.2
申请日：1980-07-30
发明人： Kitaura, Yoshihiko , Nakaguchi, Osamu , Hemmi, Keiji , Aratani, Matsuhiko , Takeno, Hidekazu , Okada, Satoshi , Tanaka, Hirokazu , Hashimoto, Masashi , Kuroda, Yoshio , Iguchi, Eiko , Kohsaka, Masanobu , Aoki, Hatsuo , Imanaka, Hiroshi
IPC分类号： C07K7/00 , C07H15/04 , C07H15/18 , A61K37/02 , C07C103/50 , C07C125/065
CPC分类号： C07C243/00 , A61K38/00 , C07K5/0215 , C07K9/005 , C12R1/465 , Y02P20/55
摘要： This invention relates to the new peptide of the general formula:
More particularly, this invention relates to this new peptide and the pharmaceutically acceptable salt thereof, which have pharmacological activities, to processesforthe preparation thereof and to a new intermediate for preparing the active peptide, and to the pharmaceutical composition comprising the same and a method of use thereof.摘要翻译： 本发明涉及通式的新的肽：
更具体地说，本发明涉及这种新的肽及其药学上可接受的盐，它们具有药理活性，到其制备方法和用于制备新的中间 活性肽，并且所述药物组合物包含相同和使用它们的方法。 -
4.发明公开
公开(公告)号：EP0050856A3
公开(公告)日：1982-08-04
申请号：EP81108796
申请日：1981-10-23
发明人： Kitaura, Yoshihiko , Nakaguchi, Osamu , Hemmi, Keiji , Aratani, Matsuhiko , Takeno, Hidekazu , Okada, Satoshi , Tanaka, Hirokazu , Hashimoto, Masashi , Kuroda, Yoshio , Iguchi, Eiko , Kohsaka, Masanobu , Aoki, Hatsuo , Imanaka, Hiroshi
IPC分类号： C07C103/52 , C07H15/04 , A61K37/02
CPC分类号： C07C243/00 , A61K38/00 , C07K5/0215 , C07K9/005
摘要： A compound of the formula or its pharmaceutically acceptable salt:
where, in one example. R' is n-octanoyl, n is the integer O, R 2 is benzyl, R 3 is 1-carboxyethylammo, R 4 is hydrogen and R 5 is hydrogen and processes for their preparation and also a pharmaceutically composition comprising, as an effective ingredient, the above compound in association with pharmaceutically acceptable carriers.-
5.发明公开New lactyl tetrapeptide, processes for preparation thereof and pharmaceutical compositions containing it 失效乳酰四肽，其制备方法和含有药物组合物的过程。
公开(公告)号：EP0011283A1
公开(公告)日：1980-05-28
申请号：EP79104479.5
申请日：1979-11-14
发明人： Kitaura, Yoshihiko , Nakaguchi, Osamu , Hemmi, Keiji , Aratani, Matsuhiko , Takeno, Hidekazu , Okada, Satoshi , Tanaka, Hirokazu , Hashimoto, Masashi , Kuroda, Yoshio , Iguchi, Eiko , Kohsaka, Masanobu , Aoki, Hatsuo , Imanaka, Hiroshi
IPC分类号： C12P21/02 , C07C103/52 , A61K37/02
CPC分类号： C12R1/465 , A61K38/00 , C07K5/0215
摘要： A lactyl tetrapeptide of the formula
can be prepared by conventional peptide synthesis. One isomer, FR 900156, is obtained by cultivation of a suitable Streptomyces strain such as Str. violaceus ATCC 31481 or Str. olivaceogriseus ATCC 31427.
The invention also relates to a pharmaceutical composition comprising, as an effective ingredient, the above compound in association with a pharmaceutically acceptable, substantially non-toxic carrier or excipient.摘要翻译： 式
的乳酰四肽可以通过常规的肽合成来制备。 一种异构体，FR 900156，通过合适的链霉菌属菌株的培养获得：如海峡菜ATCC 31481或STR Olivaceogriseus ATCC 31,427th因此，本发明涉及一种药物组合物，包括，作为有效成分，在关联的上述化合物用。 药学上可接受的，无毒的基本载体或赋形剂。 -
6.发明授权
公开(公告)号：EP0050856B1
公开(公告)日：1984-12-27
申请号：EP81108796.4
申请日：1981-10-23
发明人： Kitaura, Yoshihiko , Nakaguchi, Osamu , Hemmi, Keiji , Aratani, Matsuhiko , Takeno, Hidekazu , Okada, Satoshi , Tanaka, Hirokazu , Hashimoto, Masashi , Kuroda, Yoshio , Iguchi, Eiko , Kohsaka, Masanobu , Aoki, Hatsuo , Imanaka, Hiroshi
IPC分类号： C07C103/52 , C07H15/04 , A61K37/02
CPC分类号： C07C243/00 , A61K38/00 , C07K5/0215 , C07K9/005
-
7.发明授权New lactyl tetrapeptide, processes for preparation thereof and pharmaceutical compositions containing it 失效新的LACTYL TETRAPEPTIDE，其制备方法和含有其的药物组合物
公开(公告)号：EP0011283B1
公开(公告)日：1982-07-28
申请号：EP79104479.5
申请日：1979-11-14
发明人： Kitaura, Yoshihiko , Nakaguchi, Osamu , Hemmi, Keiji , Aratani, Matsuhiko , Takeno, Hidekazu , Okada, Satoshi , Tanaka, Hirokazu , Hashimoto, Masashi , Kuroda, Yoshio , Iguchi, Eiko , Kohsaka, Masanobu , Aoki, Hatsuo , Imanaka, Hiroshi
IPC分类号： C12P21/02 , C07C103/52 , A61K37/02
CPC分类号： C12R1/465 , A61K38/00 , C07K5/0215
-
8.发明公开
公开(公告)号：EP0025842A3
公开(公告)日：1982-02-10
申请号：EP80104502
申请日：1980-07-30
发明人： Kitaura, Yoshihiko , Nakaguchi, Osamu , Hemmi, Keiji , Aratani, Matsuhiko , Takeno, Hidekazu , Okada, Satoshi , Tanaka, Hirokazu , Hashimoto, Masashi , Kuroda, Yoshio , Iguchi, Eiko , Kohsaka, Masanobu , Aoki, Hatsuo , Imanaka, Hiroshi
IPC分类号： C07C103/52 , C07H15/04 , A61K37/02
CPC分类号： C07C243/00 , A61K38/00 , C07K5/0215 , C07K9/005 , C12R1/465 , Y02P20/55
摘要： This invention relates to the new peptide of the general formula:
More particularly, this invention relates to this new peptide and the pharmaceutically acceptable salt thereof, which have pharmacological activities, to processesforthe preparation thereof and to a new intermediate for preparing the active peptide, and to the pharmaceutical composition comprising the same and a method of use thereof.摘要翻译： 本发明涉及以下通式的新肽：
更具体而言，本发明涉及具有药理学活性的这种新肽及其药学上可接受的盐，其制备方法和用于制备的新的中间体 活性肽，以及包含其的药物组合物及其使用方法。
-
-
-
-
-
-
-
搜索结果
8 条记录 (耗时 0.023 秒)
