利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

37 条记录 (耗时 0.028 秒)

    New Cephem Compounds
    2.
    发明公开
    New Cephem Compounds 失效
    Cephemverbindungen。

    公开(公告)号：EP0517041A1

    公开(公告)日：1992-12-09

    申请号：EP92108580.9

    申请日：1992-05-21

    申请人： FUJISAWA PHARMACEUTICAL CO., LTD.

    发明人： Kawabata, Kohji ,  Okuda, Shinya ,  Yoshida, Yoshiki ,  Eikyu, Yoshiteru ,  Ogawa, Yasuhiro ,  Yamanaka, Hideaki ,  Sakane, Kazuo

    IPC分类号： C07D501/46 ,  C07D285/08 ,  A61K31/545

    CPC分类号： C07D501/00 ,  Y02P20/55

    摘要： A compound of the formula :

    wherein

    R¹ is amino or protected amino,
    R² is lower alkyl substituted with 1 to 6 halogen,
    R³ is hydroxy(lower)alkyl, protected hydroxy(lower)alkyl or halo(lower)alkyl and
    R⁴ is hydrogen, or
    R³ and R⁴ are linked together to form lower alkylene, and
    R⁵ is hydrogen or an amino protective group,
    and a pharmaceutically acceptable salt thereof, processes for their preparation and pharmaceutical compositions comprising them. The invention also relates to intermediate products of the formula

    and processes for their preparation.

    摘要翻译： 下式的化合物：其中R 1为氨基或被保护的氨基，R 2为被1至6个卤素取代的低级烷基，R 3为羟基（低级）烷基，被保护的羟基（低级） 烷基或卤代（低级）烷基，R 4是氢，或R 3和R 4连接在一起形成低级亚烷基，R 5是氢或氨基保护基，和药学上可接受的 其盐，其制备方法和包含它们的药物组合物。 本发明还涉及式CHEM的中间产物及其制备方法。 Ë

    New cephem compounds and processes for preparation thereof
    5.
    发明公开
    New cephem compounds and processes for preparation thereof 失效
    Cephemverbindungen und Verfahren zu ihrer Herstellung。

    公开(公告)号：EP0154354A2

    公开(公告)日：1985-09-11

    申请号：EP85102681.5

    申请日：1985-03-08

    申请人： FUJISAWA PHARMACEUTICAL CO., LTD.

    发明人： Takaya, Takao ,  Sakane, Kazuo ,  Yamanaka, Hideaki ,  Miyai, Kenzi

    IPC分类号： C07D501/24 ,  A61K31/545

    CPC分类号： C07D501/24

    摘要： New cephem compounds of the formula:


    wherein R' is amino or a protected amino group,
    R 2 is carboxy or a protected carboxy group, and
    X is halogen,
    and pharmaceutically acceptable salts thereof, processes for their preparation and pharmaceutical compositions containing them in association with the pharmaceutically acceptable, substantially non-toxic carrier or excipient.

    摘要翻译： 新的头孢烯化合物，其结构如下：... 其中R 1为氨基或被保护的氨基，R 2为羧基或被保护的羧基，X为卤素，和其药学上可接受的盐 其制备方法和含有它们的药物组合物与药学上可接受的，基本上无毒的载体或赋形剂相结合。

    Cephem compounds and processes for preparation thereof
    10.
    发明公开
    Cephem compounds and processes for preparation thereof 失效
    新CEPHEM化合物及其制备方法

    公开(公告)号：EP0345671A3

    公开(公告)日：1991-10-16

    申请号：EP89110068.7

    申请日：1989-06-03

    申请人： FUJISAWA PHARMACEUTICAL CO., LTD.

    发明人： Yamanaka, Hideaki ,  Yoshida, Yoshiki ,  Goto, Jiro ,  Terasawa, Takeshi ,  Okuda, Shinya ,  Sakane, Kazuo

    IPC分类号： C07D501/46 ,  A61K31/545 ,  C07D501/18

    CPC分类号： C07D501/46

    摘要： A compound of the formula :
    wherein
    R' is amino or a protected amino group, Z is N or CH, R 2 is an organic group, and R is a group of the formula :
    (in which R 3 and R 4 are each lower alkyl, or R 3 and R 4 are linked together to form C 3 -C 6 alkylene, A is lower alkylene, and R 5 is hydroxy or a protected hydroxy group) or a group of the formula :
    (in which R 6 is lower alkyl. R 7 and R 8 are each hydroxy or a protected hydroxy group, and Y is N or CH), and a pharmaceutically acceptable salt thereof, processes for their preparation and pharmaceutical compositions comprising them as an active ingredient. The invention relates also to intermediates of the formula
    and their preparation.