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公开(公告)号：EP3252171A1
公开(公告)日：2017-12-06
申请号：EP17177845.9
申请日：2014-05-22
发明人： BELLOVIN, David , BAKER, Kevin , BRENNAN, Thomas , PANDITE, Arundathy Nirmalini , MOOKERJEE, Bijoyesh , DEYOUNG, Maurice P. , KUMAR, Rakesh
CPC分类号： A61K38/179 , A61K31/337 , A61K31/519 , A61K31/555 , A61K33/24 , A61K45/06 , C07K14/71 , C07K2319/30 , C12Q1/6886 , C12Q2600/106 , C12Q2600/158 , G01N33/574 , G01N33/57496 , G01N2333/49 , G01N2333/50 , G01N2333/503 , G01N2333/515 , G01N2800/52
摘要： The invention relates to methods of treating mesothelioma comprising administering a fibroblast growth factor receptor 1 (FGFR1) extracellular domain (ECD) and/or an FGFR1 ECD fusion molecule and at least one therapeutic agent selected from pemetrexed, cisplatin, paclitaxel, carboplatin, and docetaxel are provided.
摘要翻译： 本发明涉及治疗间皮瘤的方法，其包括施用成纤维细胞生长因子受体1（FGFR1）胞外结构域（ECD）和/或FGFR1 ECD融合分子和选自培美曲塞，顺铂，紫杉醇，卡铂和多西他赛的至少一种治疗剂 被提供。
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公开(公告)号：EP2999799A2
公开(公告)日：2016-03-30
申请号：EP14800459.1
申请日：2014-05-22
发明人： BELLOVIN, David , BAKER, Kevin , BRENNAN, Thomas , PANDITE, Arundathy Nirmalini , MOOKERJEE, Bijoyesh , DEYOUNG, Maurice P. , KUMAR, Rakesh
CPC分类号： A61K38/179 , A61K31/337 , A61K31/519 , A61K31/555 , A61K33/24 , A61K45/06 , C07K14/71 , C07K2319/30 , C12Q1/6886 , C12Q2600/106 , C12Q2600/158 , G01N33/574 , G01N33/57496 , G01N2333/49 , G01N2333/50 , G01N2333/503 , G01N2333/515 , G01N2800/52
摘要： Methods of treating cancers comprising administering a fibroblast growth factor receptor 1 (FGFR1) extracellular domain (ECD) and/or an FGFR1 ECD fusion molecule are provided. Methods of treating cancers comprising administering a fibroblast growth factor receptor 1 (FGFR1) extracellular domain (ECD) and/or an FGFR1 ECD fusion molecule and at least one anti-angiogenic agent are provided.
摘要翻译： 提供了治疗癌症的方法，包括施用成纤维细胞生长因子受体1（FGFR1）胞外结构域（ECD）和/或FGFR1 ECD融合分子。 提供了治疗癌症的方法，包括施用成纤维细胞生长因子受体1（FGFR1）胞外结构域（ECD）和/或FGFR1ECD融合分子和至少一种抗血管生成剂。
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公开(公告)号：EP3964527A2
公开(公告)日：2022-03-09
申请号：EP20212116.6
申请日：2016-04-12
发明人： MASTELLER, Emma , BRENNAN, Thomas , BELLOVIN, David , BAKER, Kevin , WONG, Brian
IPC分类号： C07K16/28 , A61K39/395 , A61P35/00
摘要： Methods of treating cancer with antibodies that bind colony stimulating factor 1 receptor (CSFIR) in combination with one or more immune stimulating agents are provided.
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公开(公告)号：EP3283527A1
公开(公告)日：2018-02-21
申请号：EP16718802.8
申请日：2016-04-12
发明人： MASTELLER, Emma , BRENNAN, Thomas , BELLOVIN, David , BAKER, Kevin , WONG, Brian
IPC分类号： C07K16/28 , A61K39/395 , A61P35/00
CPC分类号： A61K47/6879 , A61K47/6851 , A61K51/1084 , A61K2039/507 , A61P35/00 , C07K16/2866 , C07K16/2878
摘要： Methods of treating cancer with antibodies that bind colony stimulating factor 1 receptor (CSF1R) in combination with one or more immune stimulating agents are provided.
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5.发明公开METHODS OF TREATING CONDITIONS WITH ANTIBODIES THAT BIND COLONY STIMULATING FACTOR 1 RECEPTOR (CSF1R) 审中-公开METHOD FOR病杂志有用于绑集落刺激因子-1受体抗体治疗（CSF1R）
公开(公告)号：EP2890398A1
公开(公告)日：2015-07-08
申请号：EP13833614.4
申请日：2013-08-30
发明人： WONG, Brian , MASTELLER, Emma , REEDQUIST, Kris , ZANGHI, James Allen , HAMBLETON, Julie , BAKER, Kevin
IPC分类号： A61K39/395 , A61P19/02 , A61P29/00 , C07K16/28 , C12Q1/48 , G01N33/564
CPC分类号： C07K16/2866 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K2317/24 , C07K2317/92 , G01N2333/52 , G01N2333/96494 , G01N2800/52
摘要： Methods of reducing cytokine levels and methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (CSF1R) are provided. Such methods include, but are not limited to, methods of treating inflammatory conditions, such as rheumatoid arthritis.
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公开(公告)号：EP3964527A3
公开(公告)日：2022-06-15
申请号：EP20212116.6
申请日：2016-04-12
发明人： MASTELLER, Emma , BRENNAN, Thomas , BELLOVIN, David , BAKER, Kevin , WONG, Brian
IPC分类号： C07K16/28 , A61K39/395 , A61P35/00
摘要： Methods of treating cancer with antibodies that bind colony stimulating factor 1 receptor (CSFIR) in combination with one or more immune stimulating agents are provided.
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7.发明公开
公开(公告)号：EP3679949A1
公开(公告)日：2020-07-15
申请号：EP19151799.4
申请日：2013-08-30
发明人： WONG, Brian , MASTELLER, Emma , REEDQUIST, Kris , ZANGHI, James Allen , HAMBLETON, Julie , BAKER, Kevin
IPC分类号： A61K39/395 , A61P19/02 , A61P29/00 , C07K16/28 , C12Q1/48 , G01N33/564
摘要： Methods of reducing cytokine levels and methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (CSF1R) are provided. Such methods include, but are not limited to, methods of treating inflammatory conditions, such as rheumatoid arthritis.
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