公开(公告)号：EP0904234B1

公开(公告)日：2002-08-28

申请号：EP97921049.9

申请日：1997-04-23

申请人： Fresenius Kabi AB

发明人： ANDERSSON, Gunnar ,  MULLIGAN, Des

IPC分类号： B65B55/02 ,  A61L2/06

CPC分类号： A61J1/10

摘要： A sealed container opening, intended for fluid communication with a container for storing medical fluids, comprising a tubular sleeve-formed part (22, 22A) having a resilient pierceable stopper (24, 24A) inserted in its mouth (21, 21A) and a covering sealing device (10, 10A). The sealed container opening contains the same autoclavable polyolefinic material as the container. All parts of said container opening, exposed to the fluid or fluid handling devices are sterilized in a signal process by means of steam transferred to these parts during its autoclavation. Saddle formed port systems attachable to a flexible container are also disclosed.

公开(公告)号：EP0961735B1

公开(公告)日：2002-09-11

申请号：EP98905914.2

申请日：1998-02-19

申请人： Fresenius Kabi AB

发明人： ANDERSSON, Gunnar ,  MULLIGAN, Des

IPC分类号： B65D41/58 ,  B65D41/50 ,  A61J1/14

CPC分类号： B29C45/14 ,  B29C35/16 ,  B29C37/005 ,  B29C45/00 ,  B29C45/0053 ,  B29C45/16 ,  B29C71/0072 ,  B29K2023/12 ,  B29L2031/565 ,  B65D51/002

摘要： The invention relates to a process of preparing pharmaceutical closures for containers made of flexible polymeric materials which are suitable to be filled with parenterally administerable fluids prior to their sealing and sterilization. The process involves a specific relaxation period for the elastomer material of the closure which thereby can settle and develop resealing characteristics. The closures will have an excellent resealing capacity after being penetrated by a piercing device for establishing fluid communication with the container, even after multiple entries into the container.